23788-85-4Relevant academic research and scientific papers
Reaction of 3-aryl-2-cyanothioacrylamides with dimethyl acetylenecarboxylate, methyl propiolate, and N-phenylmaleimide
Deryabina,Demina,Belskaya,Bakulev
, p. 2880 - 2889 (2005)
The reaction of cyanothioacrylamides with dimethyl acetylenedicarboxylate, methyl propiolate, and N-phenylmaleimide was studied. The reaction follows a cycloaddition pathway to give thiopyrans, irrespective of the electronic or spatial effects of the substituents in the thioamide group and in position 3 of the 1-thiabuta-1,3-diene system. The reaction is regio-and stereoselective.
