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DNQX, also known as 6,7-dinitroquinoxaline-2,3-dione, is a potent competitive non-NMDA glutamate receptor antagonist. It is an off-white powder with a yellow tinge, commonly used in scientific research and experiments. DNQX plays a significant role in blocking N-Methyl-D-aspartic acid (NMDA) and α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, making it a valuable tool in the study of neurological functions and disorders.

2379-57-9

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2379-57-9 Usage

Uses

Used in Pharmaceutical Research:
DNQX is used as a research chemical for studying the effects of non-NMDA glutamate receptor antagonists on neurological functions and disorders. Its ability to block NMDA and AMPA receptors makes it a valuable tool in understanding the role of these receptors in various conditions.
Used in Neurological Experiments:
DNQX is used as an experimental compound for blocking NMDA and AMPA receptors in various experiments. This application helps researchers investigate the impact of these receptors on neuronal activity and the potential therapeutic effects of targeting them in the treatment of neurological disorders.
Used in Drug Development:
DNQX is used as a lead compound in the development of new drugs targeting non-NMDA glutamate receptors. Its potent antagonistic properties make it a promising candidate for the creation of novel therapeutic agents for neurological conditions, such as epilepsy, Alzheimer's disease, and other related disorders.
Used in Quality Control and Standardization:
DNQX is used as a reference compound in the quality control and standardization of pharmaceutical products. Its well-defined chemical properties and antagonistic effects on NMDA and AMPA receptors make it an ideal standard for assessing the potency and purity of other compounds with similar activities.

Biological Activity

Water-soluble form of 6,7-Dinitroquinoxaline-2,3-dione . Selective non-NMDA receptor antagonist.

Biochem/physiol Actions

DNQX is a quinoxaline derivative.

Check Digit Verification of cas no

The CAS Registry Mumber 2379-57-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,7 and 9 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 2379-57:
(6*2)+(5*3)+(4*7)+(3*9)+(2*5)+(1*7)=99
99 % 10 = 9
So 2379-57-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14)

2379-57-9 Well-known Company Product Price

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  • Sigma

  • (D0540)  DNQX  ≥98% (TLC)

  • 2379-57-9

  • D0540-25MG

  • 885.69CNY

  • Detail
  • Sigma

  • (D0540)  DNQX  ≥98% (TLC)

  • 2379-57-9

  • D0540-50MG

  • 1,518.66CNY

  • Detail

2379-57-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 6,7-Dinitroquinoxaline-2,3-dione

1.2 Other means of identification

Product number -
Other names 6,7-dinitro-1,4-dihydroquinoxaline-2,3-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2379-57-9 SDS

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