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4-Hydroxyphenethylene glycol, also known as 4-Hydroxyphenylethylene Glycol (4-HPG), is a chemical compound with the molecular formula C8H10O3. It is a derivative of phenol, specifically a catechol, and is formed as a metabolite in the human body during the breakdown of certain neurotransmitters, such as dopamine and norepinephrine. 4-HPG is excreted in urine and can be used as a biomarker for the assessment of catecholamine metabolism and the diagnosis of certain medical conditions, including neurodegenerative diseases and psychiatric disorders. The compound is also of interest in research due to its potential role in the formation of advanced glycation end products, which are implicated in various pathological processes.

2380-75-8

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2380-75-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2380-75-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,3,8 and 0 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 2380-75:
(6*2)+(5*3)+(4*8)+(3*0)+(2*7)+(1*5)=78
78 % 10 = 8
So 2380-75-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H10O3/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4,8-11H,5H2

2380-75-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(4-hydroxyphenyl)ethane-1,2-diol

1.2 Other means of identification

Product number -
Other names 4-Hydroxyphenethylene glycol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2380-75-8 SDS

2380-75-8Downstream Products

2380-75-8Relevant academic research and scientific papers

Water-soluble constituents of coriander.

Ishikawa, Toru,Kondo, Kyoko,Kitajima, Junichi

, p. 32 - 39 (2003)

From the water-soluble portion of the methanol extract of coriander (fruit of Coriandrum sativum L.), which has been used as a spice and medicine since antiquity, 33 compounds, including two new monoterpenoids, four new monoterpenoid glycosides, two new monoterpenoid glucoside sulfates and two new aromatic compound glycosides were obtained. Their structures, were clarified by spectral investigation.

Facile synthesis of glycol metabolites of phenethylamine drugs

Holshouser,Kolb

, p. 619 - 621 (2007/10/02)

High yields of potential glycol metabolites of p-synephrine, epinephrine, octopamine, and normacromerine can be obtained from the readily available monosubstituted and disubstituted acetophenones. The general procedure involves alpha-bromination followed by displacement with acetate ion and reduction with lithium aluminum hydride. Yields ranged from 46 to 91%. Furthermore, the procedure minimizes some problems inherent in aromatic glycol synthesis which include dimerization and pinacol-pinacolone rearrangement.

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