23808-43-7 Usage
Uses
Used in Pharmaceutical Industry:
1-(4-Fluorophenethyl)-4-piperidone is used as an intermediate in the synthesis of various pharmaceuticals for its potential psychoactive and analgesic properties. Its role in the development of new medications is significant, as it can contribute to the creation of drugs that target specific conditions requiring such effects.
Used in Research Chemicals:
In the realm of research chemicals, 1-(4-Fluorophenethyl)-4-piperidone is utilized as a precursor, enabling the production of designer drugs. Its use in this context is crucial for the exploration of new chemical entities and their potential applications in medicine and other fields.
Used in Psychopharmacological Research:
1-(4-Fluorophenethyl)-4-piperidone is used as a subject of research in psychopharmacology to investigate its stimulating effects on the central nervous system. Understanding its impact can lead to advancements in the treatment of neurological and psychological disorders.
Used in Toxicological Studies:
As a controlled substance with potential addictive properties, 1-(4-Fluorophenethyl)-4-piperidone is also used in toxicological studies to determine its safety profile and potential risks associated with its use. This research is vital for establishing guidelines and regulations regarding its application and handling.
Check Digit Verification of cas no
The CAS Registry Mumber 23808-43-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,8,0 and 8 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 23808-43:
(7*2)+(6*3)+(5*8)+(4*0)+(3*8)+(2*4)+(1*3)=107
107 % 10 = 7
So 23808-43-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H16FNO/c14-12-3-1-11(2-4-12)5-8-15-9-6-13(16)7-10-15/h1-4H,5-10H2
23808-43-7Relevant academic research and scientific papers
New antihistaminic N-heterocyclic 4-piperidinamines. 1. Synthesis and antihistaminic activity of N-(4-piperidinyl)-1H-benzimidazol-2-amines
Janssens,Torremans,Janssen,Stokbroekx,Luyckx
, p. 1925 - 1933 (2007/10/02)
The synthesis of a series N-(4-piperidinyl)-1H-benzimidazol-2-amines and the preliminary evaluation of their in vitro and in vivo antihistaminic activity are described. Cyclodesulfurization of (2-aminophenyl) thioureas with mercury(II) oxide resulted in 2-aminobenzimidazole intermediates, which were monoalkylated on the endo-nitrogen atom. After deprotection of the piperideine nitrogen atom with 48% aqueous hydrobromic acid solution, the title compounds were obtained by three different methods, viz. alkylation, reductive amination, or oxirane ring-opening reactions. The in vivo antihistaminic activity was evaluated by the compound 48/80 induced lethality test in rats and histamine-induced lethality test in guinea pigs after oral and/or subcutaneous administration. The duration of action, for a selected number of compounds, was studied in the guinea pig. The phenylethyl derivatives showed the most potent antihistamine properties after oral administration in both animal species.
