23809-33-8

Usage

Uses

Used in Organic Synthesis:
2,2-Dimethylpropanal carbamoyl hydrazone is used as a reagent in organic synthesis for the preparation of various derivatives, contributing to the development of new chemical compounds and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,2-Dimethylpropanal carbamoyl hydrazone is utilized as a starting material for the synthesis of potential drug candidates, playing a crucial role in the discovery and development of new medications.
Used in Corrosion Inhibition:
2,2-Dimethylpropanal carbamoyl hydrazone has been investigated for its potential use as a corrosion inhibitor in metal surfaces, offering a protective layer against environmental factors that can cause degradation and wear.

InChI:InChI=1/C6H13N3O/c1-6(2,3)4-8-9-5(7)10/h4H,1-3H3,(H3,7,9,10)

Upstream product

• 563-41-7 semicarbazide hydrochloride 
• 62993-79-7 1-(1-adamantyl)-3-tert-butylaziridinone 

Downstream Products

• 563-80-4 3-methyl-butan-2-one 
• 69741-92-0 5-tert-butyl-[1,3,4]oxadiazol-2-ylamine 

Relevant academic research and scientific papers

A direct link between the Passerini reaction and α-lactams

α-Lactams (aziridinones) can function to replace two of the three reactants, the oxo-compound and the isonitrile, in the Passerini reaction. Four α-lactams (5a-d) were reacted with mono- and dicarboxylic acids of positive pKa values to give 2-acyloxycarboxamides (4) and bis-2-acyloxycarboxamide products 12 and 13, respectively. The same compounds were also prepared via the Passerini reaction. Acids with a negative pK a decarbonylate α-lactams to give immonium salts. The main path of the reaction depends on the pKa of the acid component, the reactivity of the α-lactam, and the reaction conditions.

The synthesis, physical, and spectral properties, and some reactions of a new stable bis-α-lactam (aziridinone) with a terpene skeleton

A synthesis of a new stable bis-α-lactam, cis-1,1′(p-menth-1,8-ylene) bis(3-tert-butyl-2-azirididone) (4), derived from p-menthane, is described. Complete spontaneous thermal decomposition required lh of reflux in boiling n-decane (b.p. 174°C) and the products are 2,2-dimethylpropanal (pivalaldehyde) (6) and 1,8-diisocyano-p-menthane (7). Reaction with benzylamine yielded the unexpected bis-benzylamide (13a), while reaction with sodium methoxide gave the bisα-amino acid ester (14).