2382-64-1

Usage

Uses

Used in Pharmaceutical Industry:
Uridine, cytidylyl-(3'→5')is utilized as a therapeutic agent for its potential to address neurodegenerative disorders. Uridine, cytidylyl-(3'®5')-'s involvement in cellular processes and energy production suggests it may support neuronal health and function, offering a potential avenue for treatment or mitigation of disease progression.
Used in Cognitive Enhancement Applications:
In the field of cognitive enhancement, Uridine, cytidylyl-(3'→5')is employed to potentially improve cognitive function. Its role in the biosynthesis of RNA and energy production may contribute to enhancing brain health and cognitive performance, making it a candidate for supplements or therapies aimed at boosting cognitive abilities.
Used in Research and Development:
Uridine, cytidylyl-(3'→5')serves as a key component in biological research, particularly in studies focused on the mechanisms of RNA synthesis, genetic information transfer, and cellular energy metabolism. Its presence in experiments allows scientists to investigate the fundamental processes of life and develop a deeper understanding of cellular functions and their implications in health and disease.

Downstream Products

• 633-90-9 cytidine 2',3'-cyclic monophosphate 
• 58-96-8 uridine 

Relevant academic research and scientific papers

Chemical synthesis of RNA via 2′-O-cyanoethylated intermediates

It was found that 2′-O-cyanoethyl group could be removed from 2′-O-cyanoethylated ribonucleoside derivatives by treatment with Bu4NF. This finding was successfully applied to the synthesis of oligoribonucleotides via their 2′-O-cyanoethylated derivatives as key intermediates where a cyanoethyl group was used as the 2′-hydroxyl protecting group. The rate of condensation using this protecting group in the presence of various activators was generally faster than that observed when a TBDMS group was used as the protecting group.

Some observations relating to the use of 1-aryl-4-alkoxypiperidin-4-yl groups for the protection of the 2′-hydroxy functions in the chemical synthesis of oligoribonucleotides

The comparative rates of acid-catalysed removal often 1-aryl-4-methoxypiperidin-4-yl 8 (R = Me) [including the previously reported Ctmp 5 and Fpmp 6] protecting groups for the 2′-hydroxy functions in oligoribonucleotide synthesis are discussed. These studies have led to the development of the 1-(4-chlorophenyl)-4-ethoxypiperidin-4-yl (Cpep) protecting group 8 (R = Et, R1 = R2 = H, R3 = Cl) which is both more stable than the Ctmp and Fpmp groups at pH 0.5 and more labile at pH 3.75. The influence of the ribonucleoside aglycone on the stability of the 2′-O-Fpmp and 2′-O-Ctmp protecting groups both at low and high pH is examined. The Royal Society of Chemistry 2000.