23826-59-7

Upstream product

• 626-55-1 3-Bromopyridine 
• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 92200-20-9 α-[3]Pyridyl-mandelsaeure-methylester 

Downstream Products

• 205323-22-4 Methanesulfonic acid 1-morpholin-4-yl-3-phenyl-1H-pyrrolo[2,3-b]pyridin-2-yl ester 
• 155705-83-2 3-Methanesulfonyl-1-morpholin-4-yl-3-phenyl-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one 
• 155705-82-1 2-hydroxy-N-(4-morpholinyl)-2-phenyl-2-(3-pyridinyl)-acetamide 

Relevant academic research and scientific papers

Synthesis and Unexpected Reactions of 2-Hydroxy-3-pyridinylacetic Hydrazides. Formation of 2H-Pyrrolo[2,3-b]pyridin-2-ones

Treatment of 2-hydroxy-3-pyridinylacetic hydrazides under mild mesylation conditions provided 2H-pyrrolo[2,3-b]pyridin-2-ones as unexpected products. This rearrangement is believed to result from an intramolecular attack of the hydrazide on a reactive pyridinium species formed under the reaction conditions.

1-substituted oxindoles as cognition enhancers

Compounds of Formula I have been shown to enhance the release of the neurotransmitter acetlcholine, and thus may be useful as chemical intermediates and as pharmacological agents in the treatment of diseases of man, such as in Alzheimer's Disease and othe