23834-01-7

Basic information

• Product Name: 4,5,7-Trichloro Quinoline
• Synonyms: 4,5,7-Trichloro Quinoline;BUTTPARK 177\09-89
• CAS NO: 23834-01-7
• Molecular Formula: C₉H₄Cl₃N
• Molecular Weight: 232.49376
• EINECS: 1533716-785-6
• Mol File: 23834-01-7.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 327oC
• Flash Point: 181.2oC
• Appearance: Type white crystalline powders
• Density: 1.523±0.06 g/cm3 (20 ºC 760 Torr)
• Vapor Pressure: 0.000405mmHg at 25°C
• Refractive Index: 1.667
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Sparingly), Toluene (Slightly, Sonicated)
• CAS DataBase Reference: 4,5,7-Trichloro Quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4,5,7-Trichloro Quinoline(23834-01-7)
• EPA Substance Registry System: 4,5,7-Trichloro Quinoline(23834-01-7)

Safety Data

• Hazard Codes: T
• Statements: 25-41
• Safety Statements: 26-39-45
• Hazardous Substances Data: 23834-01-7(Hazardous Substances Data)

Usage

Uses

4,5,7-Trichloroquinoline is an intermediate in synthesizing Quinoxyfen-d4 (Q765502), an isotope labelled Quinoxyfen acts as an agricultural fungicide.

InChI:InChI=1/C9H4Cl3N/c10-5-3-7(12)9-6(11)1-2-13-8(9)4-5/h1-4H

Upstream product

• 626-43-7 3,5-Dichloroaniline 
• 131123-76-7 5,7-dichlorokynurenic acid 
• 157848-08-3 5,7-dichloro-4-hydroxy-quinoline-2-carboxylic acid ethyl ester 
• 33149-04-1 β-(3,5-dichloroanilino)propionitrile 
• 171850-29-6 4-hydroxy-5,7-dichloroquinoline 

Downstream Products

• 5437-27-4 N⁴,N⁴-diethyl-N¹-(5,7-dichloro-[4]quinolyl)-1-methyl-butanediyldiamine 
• 124495-18-7 5,7-dichloro-4-(4-fluorophenoxy)quinoline 

Relevant articles and documents

4. The preparation method of the 5, 7 - trichloro quinoline (by machine translation)

The invention discloses 4, 5, 7 - trichloro quinoline of the preparation method, it [...] shown (I) 5, 7 - dichloro - 2, 3 - dihydro-quinoline - 4 (1 H) - one dissolved in reagent chloride and 1st in the organic solvent, at a temperature of 80 - 120 °C reaction under 10 - 17 h, after the reaction, the reaction liquid is post-processed to obtain the formula (II) as shown in the 4, 5, 7 - trichloro quinoline; reaction as follows: . The invention through one-step will be 5, 7 - dichloro - 2, 3 - dihydro-quinoline - 4 (1 H) - one obtained by synthesizing 4, 5, 7 - trichloro quinoline, this method has the advantages of simple, efficient, yield and low cost. (by machine translation)

Process to produce halo-4-phenoxyquinolines

The present invention relates to a process for the preparation of halo-4-phenoxyquinolines.

Catalytic enantioselective reissert-type reaction: Development and application to the synthesis of a potent NMDA receptor antagonist (-)-L-689,560 using a solid-supported catalyst

Full details of the first catalytic enantioselective Reissert-type reaction are described. Utilizing the Lewis acid-Lewis base bifunctional catalyst 5 or 6 (9 mol %), the Reissert products were obtained in 57 to 99% yield with 54 to 96% ee. Electron-rich