23844-56-6Relevant articles and documents
Insight into solid-liquid phase transfer catalyzed synthesis of Mecoprop ester using K 2CO 3 as base and development of new kinetic model involving liquid product and two solid co-products
Yadav, Ganapati D,Deshmukh, Gunjan P
, p. 1677 - 1685 (2017)
Abstract: 2-Methyl-4-chlorophenoxy propionic acid (Mecoprop) is a widely used household herbicide. In the current work, a simple synthetic method is developed for Mecoprop methyl ester using solid-liquid phase transfer catalysis (S-L PTC) with K 2CO 3 as mild base and toluene as solvent. Conversion of 95% was achieved with 100% selectivity for Mecoprop ester at 100°C. Simple isolation process was employed to recover the product from the reaction mixture. A reaction mechanism was proposed and new kinetic model developed involving one liquid and two solid co-products. The activation energy for the reaction was calculated. This is the first example of its kind being reported vis-à-vis kinetics and mechanism. Graphical Abstract: Solid-liquid phase transfer catalyzed (S-L PTC) O-alkylation of 4-chloro-2-methyl phenol is done at relatively mild conditions to form methyl 2-(4-chloro-2-methylphenoxy) propionate (Mecoprop methyl ester). New insight on reaction mechanism and kinetics is presented.
Preparation of aliphatic/aromatic ethers
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, (2008/06/13)
Aliphatic/aromatic ethers are prepared by reacting an aliphatic halide with either an alkali or alkaline earth metal, or ammonium phenolate or naphtholate, in an inert organic solvent, and in the presence of at least one tertiary amine sequestering agent having the formula:
