2385-28-6

Usage

Uses

Used in Organic Synthesis:
2,3-Piperazinedione,1-butyl-(7CI,9CI) is used as a versatile intermediate for the synthesis of various compounds, contributing to the development of new organic molecules.
Used in Pharmaceutical Production:
2,3-Piperazinedione,1-butyl-(7CI,9CI) is used as a key component in the production of pharmaceuticals, playing a crucial role in the synthesis of drugs with potential therapeutic applications.
Used in Agrochemical Production:
2,3-Piperazinedione,1-butyl-(7CI,9CI) is used as a building block in the synthesis of agrochemicals, aiding in the development of new compounds for agricultural applications.
Used in Material Science:
2,3-Piperazinedione,1-butyl-(7CI,9CI) is used as a potential building block for the development of novel materials and polymers, expanding the scope of materials available for various industries.
Used in Medicinal Chemistry and Drug Discovery:
2,3-Piperazinedione,1-butyl-(7CI,9CI) is used as a scaffold for the design of new compounds with biological activity, contributing to the advancement of drug discovery and the development of new therapeutic agents.

InChI:InChI=1/C8H14N2O2/c1-2-3-5-10-6-4-9-7(11)8(10)12/h2-6H2,1H3,(H,9,11)

Upstream product

• 13880-27-8 trans-1,2-diaminohexane 
• 95-92-1 oxalic acid diethyl ester 
• 1375301-09-9 C₁₅H₂₀N₂O₂ 
• 19522-69-1 N-butylethylenediamine 

Downstream Products

• 1015005-45-4 methyl (4-butyl-2,3-dioxopiperazin-1-yl)(phenyl)acetate 

Relevant academic research and scientific papers

PIPERIDINE AND PYRROLIDINE BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

The present invention is directed to compounds of formula (I) which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.

N-(3-amino-2-hydroxy-propyl) substd. alkylamidoalkanol compd.

Disclosed are compounds of the formula (I): useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

Aspartyl protease inhibitors

The present invention provides compounds having the formula: wherein R1, R′, R2, R3, R3′, R4, X1, X2 and X3 are as defined herein, and pharmaceutical compositions thereof. The present invention also provides methods of inhibiting proteases, more specifically aspartyl proteases. In certain embodiments, compounds inhibit BACE (β-site APP-cleaving enzyme), and thus are useful in the treatment or prevention of a disease characterized by β-amyloid deposits in the brain (including, but not limited to, Alzheimer's Disease). The present invention also provides methods for preparing compounds of the invention.

ASPARTYL PROTEASE INHIBITORS

The present invention provides compounds having formula (I): wherein R’, R0, R1, X1, R2, R3, R3’, X2, X3, and R4 are as defined herein, and pharmaceuticals compositions thereof. The present invention also provides methods of inhibiting proteases, more specially aspartyl proteases. In certain embodiments, compounds inhibit BACE (β-site APP-cleaving enzyme), and thus are useful in the treatment or prevention of a disease characterized by β-amyloid deposits in the brain (including, but not limited to, Alzheimer’s Disease). The present invention also provides methods for preparing compounds of the invention.