23856-27-1

Basic information

• Product Name: 1-[(p-Chlorophenoxy)acetyl]-1H-indazol-5-amine
• Synonyms: 1-[(p-Chlorophenoxy)acetyl]-1H-indazol-5-amine;1-(5-Amino-1H-indazol-1-yl)-2-(4-chlorophenoxy)ethanone
• CAS NO: 23856-27-1
• Molecular Formula: C15H12 Cl N3 O2
• Molecular Weight: 301.7277
• Mol File: 23856-27-1.mol
• Article Data: 0

Chemical Properties

• Melting Point: 159 °C
• Boiling Point: 540.5°Cat760mmHg
• Flash Point: 280.7°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 9.52E-12mmHg at 25°C
• Refractive Index: 1.668
• PKA: 2.96±0.10(Predicted)
• CAS DataBase Reference: 1-[(p-Chlorophenoxy)acetyl]-1H-indazol-5-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(p-Chlorophenoxy)acetyl]-1H-indazol-5-amine(23856-27-1)
• EPA Substance Registry System: 1-[(p-Chlorophenoxy)acetyl]-1H-indazol-5-amine(23856-27-1)

Safety Data

• Hazardous Substances Data: 23856-27-1(Hazardous Substances Data)

Usage

Chemical class

Indazole derivative

Structural feature

Contains a chlorophenyl group attached to the acetyl side chain

Target enzyme

Platelet-activating factor acetylhydrolase (PAF-AH)

Enzyme inhibition

Potent inhibitor of PAF-AH

Implications

Involved in inflammatory and allergic diseases

Therapeutic potential

Possible treatment for inflammatory and allergic conditions by modulating PAF-AH activity

Further investigation

May have other biological activities and potential therapeutic applications
These properties and contents provide a comprehensive overview of the chemical compound 1-[(p-Chlorophenoxy)acetyl]-1H-indazol-5-amine, its structure, and its potential applications in the treatment of various diseases.

InChI:InChI=1/C15H12ClN3O2/c16-11-1-4-13(5-2-11)21-9-15(20)19-14-6-3-12(17)7-10(14)8-18-19/h1-8H,9,17H2