2386-54-1

Basic information

• Product Name: Sodium 1-butanesulfonate
• Synonyms: IPC-ALKS-4;BUTYLSULFONIC ACID SODIUM SALT;BUTANE 1-SULFONIC ACID SODIUM SALT;BUTANE-1-SULPHONIC ACID SODIUM SALT;sodium butane-1-sulphonate;1-BUTANESULFONIC ACID SODIUM SALT CONC., FOR IPC, 6 AMP.;1-BUTANESULFONIC ACID SODIUM SALT MONOHH YDRATE;1-BUTANESULFONIC ACID SODIUM
• CAS NO: 2386-54-1
• Molecular Formula: C₄H₉O₃S*Na
• Molecular Weight: 160.17
• EINECS: 219-201-1
• Product Categories: Analytical Chemistry;HPLC Ion-Pair Reagents for Basic Samples;Ion-Pair Reagents for HPLC;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfonic/Sulfinic Acid Salts;Sulfur Compounds
• Mol File: 2386-54-1.mol
• Article Data: 5

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: White to off-white/Crystalline Powder
• Density: 1.221g/cm3
• Storage Temp.: Store below +30°C.
• Solubility: H2O: 0.1 g/mL, clear to slightly hazy
• Water Solubility: soluble
• BRN: 3716662
• CAS DataBase Reference: Sodium 1-butanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: Sodium 1-butanesulfonate(2386-54-1)
• EPA Substance Registry System: Sodium 1-butanesulfonate(2386-54-1)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 37/39-26-36
• WGK Germany: 3
• F: 8-10-23
• TSCA: Yes
• Hazardous Substances Data: 2386-54-1(Hazardous Substances Data)

Usage

Chemical Properties

white to off-white crystalline powder

Uses

Different sources of media describe the Uses of 2386-54-1 differently. You can refer to the following data:
1. suzuki reaction
2. Sodium 1-butanesulfonate was used in the synthesis of high silicon content SAPO4-5. It was also used as a mobile phase to separate eight selenium compounds (selenite, selenate, selenocystine, selenourea, selenomethionine, selenoethionine, selenocystamine and trimethylselenonium ion). Ion-associating reagent for HPLC1 and reversed-phase chromatography.

General Description

Sodium 1-butanesulfonate is an anionic detergent.

Biochem/physiol Actions

Sodium 1-butanesulfonate can be used in the preparation of mobile phase for high performance liquid chromatography-inductively coupled plasma-mass spectrometry (HPLC-ICP-MS).

InChI:InChI=1/C4H10O3S/c1-2-3-4-8(5,6)7/h2-4H2,1H3,(H,5,6,7)/p-1

Upstream product

• 542-69-8 1-iodo-butane 
• 109-69-3 n-Butyl chloride 
• 109-65-9 1-bromo-butane 
• 72500-12-0 Trimethylsilyl-1-butansulfonat 
• 2386-60-9 perfluoro-1-butanesulfonyl fluoride 

Downstream Products

• 639007-38-8 N-benzyl-2-(butane-1-sulfonyl)-acetamide 
• 1293990-63-2 2-phenyl-9-tetradecyl-benzo[8,9]quinolizino[4,5,6,7-fed]phenanthridinylium butanesulfonate 
• 2386-60-9 perfluoro-1-butanesulfonyl fluoride 

Relevant articles and documents

Preparation of sodium sulfonates using by copper as catalyst

The sodium alkyl sulfonates were prepared by Strecker reaction. The synthesis of sodium chloroethyl sulfonate from dichloroethane and sodium sulfite with different catalysts, it was found that copper was an efficient catalyst with a yield (81%). The reaction conditions were also optimized to make the route more competitive and suitable for large-scale industrial production. Besides, some more sulfonates were also obtained with copper as catalyst via Strecker reaction.

Synthesis of Aromatic and Olefinic Sodium Sulfonates by Electrophilic Destannylation with Trimethylsilyl Chlorosulfonate

A mild and effective method for the preparation of a variety of aromatic, olefinic, and acetylenic sodium sulfonates is described.The reaction of trialkylaryl- (2a-k) and -heteroarylstannanes (4a-d), bis-(1-alkenyl)dibutylstannanes (6a-f), or trialkylakynylstannanes with trimethylsilyl chlorosulfonate (1) followed by hydrolysis with aqueous NaHCO3 provides the sodium sulfonates in an ipso-specific and in the case of vinylic stannanes stereospecific manner.A comparision of the reactivity of stannylated and silylated olefinic compounds 13 and 14 underlines the greater leaving ability of the stannyl moiety.The in situ preparation of the stannanes makes it possible to apply the synthetic method to natural products such as N-substituted apocodeine (17). - Key Words: Electrophilic aromatic substitution/ Electrophilic vinylic substitution/ Trialkylstannanes, application of/ Arylsulfonates, sodium salts of/ Vinylsulfonates, sodium salts of

Studies on Sulphochlorination of Paraffins. VIII. Studies on the Hydrolysis of Individual Alkane Sulphochlorides by Sodium Hydroxide

The hydrolysis of individual C1-C5 alkane sulphochlorides by sodium hydroxide in dioxane/water (1:1) was kinetically studied at 25 deg C by means of stopped-flow technique, measuring the change of electric conductivity.The rate constants were influenced by steric hindrance, but in all cases were higher than the rate constant for alkaline hydrolysis of benzene sulphochloride, which cannot react according to the elimination-addition (sulphene) mechanism.The reaction enthalpy of the alkaline hydrolysis of four individual alkane sulphochlorides was determined by a simple calorimetric apparatus; the average value amounts to ΔRH = -239 kJ mol-1.