23869-15-0Relevant articles and documents
Substituted bridged phenyl piperidines: Orally active growth hormone secretagogues
Lu, Zhijian,Tata, James R.,Cheng, Kang,Wei, Liente,Chan, Wanda W.-S.,Butler, Bridget,Schleim, Klaus D.,Jacks, Thomas M.,Hickey, Gerard,Patchett, Arthur A.
, p. 1817 - 1820 (2007/10/03)
A new series of growth hormone secretagogues have been discovered. The best compound, 26j, shows excellent ability to release growth hormone both in vitro and in vivo. The synthesis and biological activity of these compounds are discussed.
[2]Benzopyrano[3,4-c]pyridines and process therefor
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, (2008/06/13)
[2]Benzopyrano[3,4-c]pyridine derivatives characterized by having a 2,3,4,4a,6,10b-hexahydro-1H-[2]benzopyrano[3,4-c]pyridine nucleus bearing a substituent at position 6 are disclosed. The nucleus can be optionally further substituted at positions 2,3,4,6 and on the aromatic ring. The derivatives are useful diuretic, anorexic, antidepressant, anticonvulsant and antihypertensive agents. Methods for their preparation and use also are disclosed.