238748-91-9

Upstream product

• 18880-04-1 3,4-dichlorobenzyl bromide 
• 46193-76-4 ethyl 4H-thieno[3,2-b]pyrrole-5-carboxylate 

Downstream Products

• 238749-23-0 4-(3,4-Dichlorobenzyl)thieno[3,2-b ]pyrrole-5-carboxylic acid 

Relevant academic research and scientific papers

BICYCLIC PYRROLE DERIVATIVES AS MCP-1 INHIBITORS

A pharmaceutical composition comprising a compound of formula (I):or a pharmaceutically acceptable salt, ester or amide thereof, which is an inhibitor of monocyte chemoattractant protein-1 and wherein A and B together form an optionally substituted 5-member aromatic ring which includes at least one heteroatom; R1 is an optionally substituted aryl or heteroaryl ring; R2 is selected from a range of organic groups including carboxy, and R3 is hydrogen, or a range of organic groups; in combination with a pharmaceutically acceptable carrier. Certain compounds of formula (I) are novel and these form a further aspect of the invention.

Bicyclic pyrrole derivatives as MCP-1 inhibitors

A pharmaceutical composition comprising a compound of formula (I): or a pharmaceutically acceptable salt, ester or amide thereof, which is an inhibitor of monocyte chemoattractant protein-1 and wherein A and B together form an optionally substituted 5-member aromatic ring which includes at least one heteroatom; R1is an optionally substituted aryl or heteroaryl ring; R2is selected from a range of organic groups including carboxy, and R3is hydrogen, or a range of organic groups; in combination with a pharmaceutically acceptable carrier. Certain compounds of formula (I) are novel and these form a further aspect of the invention.