23876-18-8Relevant academic research and scientific papers
Hexahydro-cyclohepta-pyrrole oxindole as potent kinase inhibitors
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Page/Page column 22, (2010/02/08)
The present invention is directed to a class indolinone compounds, hexahydro-cyclohepta-pyrrole oxindoles, which are useful as protein kinase inhibitors.
Prodrugs of a 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
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, (2008/06/13)
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
Combination therapy for the treatment of cancer
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, (2008/06/13)
The present invention relates to methods for treatment or prevention of neoplasia disorders using protein tyrosine kinase inhibitors in combination with cyclooxygenase inhibitors, in particular cyclooxygenase-2 selective inhibitors.
Pyrrole substituted 2-indolinone protein kinase inhibitors
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, (2008/06/13)
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
3-heteroarylidene-2-indolinone protein kinase inhibitors
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, (2008/06/13)
The present invention relates to novel 3-heteroarylidene-2-indolinone compounds and physiologically acceptable salts thereof which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
3-(cycloalkanoheteroarylidenyl)-2-indolinone protein tyrosine kinase inhibitors
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Page column 19-20, (2010/02/05)
The present invention relates to novel 3-(cycloalkano-heteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.
3-(cycloalkanoheteroarylidenyl)-2- indolinone protein tyrosine kinase inhibitors
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, (2008/06/13)
The present invention relates to novel 3-(cycloalkanoheteroarylidenyl)-2-indolinone compounds and physiologically acceptable salts and prodrugs thereof which are expected to modulate the activity of protein tyrosine kinases and therefore to be useful in the prevention and treatment of protein tyrosine kinase related cellular disorders such as cancer.
