23877-63-6

Basic information

• Product Name: 2-(1-methylvinyl)benzonitrile
• Synonyms: 2-(1-methylvinyl)benzonitrile
• CAS NO: 23877-63-6
• Molecular Weight: 143.188
• Mol File: 23877-63-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-(1-methylvinyl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-methylvinyl)benzonitrile(23877-63-6)
• EPA Substance Registry System: 2-(1-methylvinyl)benzonitrile(23877-63-6)

Safety Data

• Hazardous Substances Data: 23877-63-6(Hazardous Substances Data)

Upstream product

• 2042-37-7 o-cyanobromobenzene 
• 91054-33-0 2-acetylbenzonitrile 
• 19493-09-5 Methylenetriphenylphosphorane 
• 108-22-5 Isopropenyl acetate 
• 873-32-5 2-Chlorobenzonitrile 
• 14559-87-6 isopropenylboronic acid 

Relevant articles and documents

Chiral Aluminum Complex Controls Enantioselective Nickel-Catalyzed Synthesis of Indenes: C?CN Bond Activation

A chiral aluminum complex controlled, enantioselective nickel-catalyzed domino reaction of aryl nitriles and alkynes proceeding by C?CN bond activation was developed. The reaction provides various indenes, bearing chiral all-carbon quaternary centers, under mild reaction conditions in yields of 32 to 91 percent and ee values within the 73–98 percent range. The reaction mechanism and aspects of stereocontrol were investigated by DFT calculations.

Cobalt-catalyzed vinylation of functionalized aryl halides with vinyl acetates

A new method for the preparation of styrene derivatives is described on the basis of the activation of aryl halides by low-valent cobalt species. A combination of CoII bromide and 2,2′-bipyridine is suitable as catalyst for the cross-coupling reaction of a wide range of aromatic halides (X = Cl, Br, I), mostly bearing sensitive moieties, with vinyl acetates. These reactions proceed under mild conditions in the presence of the appropriate reducing agent to afford α-substituted styrene compounds in satisfactory to high yields. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.

Suzuki cross-coupling reactions between alkenylboronic acids and aryl bromides catalysed by a tetraphosphane-palladium catalyst

A range of alkenylboronic acids undergo Suzuki cross-coupling with aryl bromides in good yields in the presence of [PdCl(C3H 5)]2/cis,cis,cis-1,2,3,4-tetrakis[(diphenylphosphanyl) methyl]cyclopentane as a catalyst. A wide variety of 1-arylprop-1-enes, 2-arylprop-1-enes, 2-arylbut-1-enes and 1,1-diarylethylene or styrene derivatives have been prepared. Moreover, the reaction tolerates several functions, such as acetyl, formyl, nitrile or nitro. Furthermore, this catalyst can be used at low loading, even for reactions of sterically hindered substrates. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.