2388-43-4Relevant academic research and scientific papers
Syntheses of Calixnaphthalenes Derived from 1-Naphthol
Georghiou, Paris E.,Ashram, Muhammad,Li, Zhaopeng,Chaulk, Steven G.
, p. 7284 - 7289 (1995)
Using a convergent synthetic strategy, the synthesis of the previously elusive C4ν-symmetrical calixnaphthalene from 1-naphthol is described.Using other independent convergent routes, syntheses of the other three isomeric calixnaphthalenes originally formed from the direct base-catalyzed condensation of formaldehyde with 1-naphthol are also described.All of these methods involved either a TiCl4- or TFA-assisted coupling reaction to achieve the cyclization steps.A mechanism is proposed to account for the formation of the original three isomeric calixnaphthalenes from the base-catalyzed condensation of formaldehyde with 1-naphthol.
N-benzotriazoles: Preparation and Use in Synthesis
Katritzky, Alan R.,Lan, Xiangfu,Lam, Jamshed N.
, p. 1819 - 1826 (2007/10/02)
Methoxybenzenes and -naphthalenes are benzotriazolylmethylated in the para-position or if this is blocked in an ortho-position.The methylene groups in the products are readily substituted by electrophiles via the lithiated derivatives.Displacement ot the benzotriazole group can be effected by organometallic reagents or by electron-rich benzoid compounds to afford a versatile method for the synthesis of substituted aryl ethers.Key Words: Lithiation/ Grignard reaction/ Condensation/ Aryl ethers/ Diarylmethanes
