23899-79-8

Basic information

• Product Name: 5-amino-1-methylpyrimidine-2,4(1H,3H)-dione
• CAS NO: 23899-79-8
• Molecular Formula: C₅H₇N₃O₂
• Molecular Weight: 141.128
• Mol File: 23899-79-8.mol
• Article Data: 2

Chemical Properties

• Density: 1.339g/cm³
• Refractive Index: 1.548
• CAS DataBase Reference: 5-amino-1-methylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-1-methylpyrimidine-2,4(1H,3H)-dione(23899-79-8)
• EPA Substance Registry System: 5-amino-1-methylpyrimidine-2,4(1H,3H)-dione(23899-79-8)

Safety Data

• Hazardous Substances Data: 23899-79-8(Hazardous Substances Data)

Usage

General Description

5-amino-1-methylpyrimidine-2,4(1H,3H)-dione is a chemical compound that belongs to the class of pyrimidine derivatives. It is a white, crystalline solid that is commonly used in the synthesis of pharmaceuticals and pesticides. 5-amino-1-methylpyrimidine-2,4(1H,3H)-dione has a range of applications in the pharmaceutical industry due to its ability to act as a building block for the synthesis of various drugs. Additionally, it has been shown to exhibit antiviral, antitumor, and anti-inflammatory properties, making it a valuable chemical in the development of new medications. The compound is also known for its relatively low toxicity, making it a preferred ingredient in pharmaceutical research and development.

Upstream product

• 6972-77-6 N-cyanoacetyl-N'-methyl-urea 
• 28495-88-7 1-methyl-5-nitrouracil 

Relevant articles and documents

Preparation method of theobromine

The invention discloses a preparation method of theobromine, and relates to the technical field of preparation of heterocyclic compounds containing purine ring systems. The method comprises the following steps: adding oxalyl chloride into cyanoacetic acid and a solvent at the temperature of -10-20 DEG C, concentrating to remove the solvent and oxalyl chloride after reaction, adding monomethylureaand the solvent at the temperature of 0-30 DEG C, adding alkali as an acid-binding agent, adding water after reaction, stirring, and filtering to obtain monomethyl cyanoacetylurea; adding water to dissolve cyanuric chloride, adding liquid caustic soda to adjust the pH value to 8-11, and reacting at 80-100 DEG C to generate methyl 4AU; dissolving monomethyl 4AU in formic acid, adding sodium nitrite, reacting at room temperature, adding a catalyst, keeping the temperature at 30-70 DEG C, recovering the catalyst after the reaction is finished, and concentrating mother liquor to recover formic acid, thereby obtaining monomethyl FAU; adding water and liquid caustic soda into monomethyl FAU, carrying out ring-closure reaction, and then adding acid to adjust to be neutral, so as to obtain 3-methyl xanthine; and carrying out a methylation reaction on 3-methylxanthine, and refining to obtain theobromine. The method has the advantages of few reaction steps, few side reactions, high yield and stable product quality.