23899-79-8

Usage

Uses

Used in Pharmaceutical Industry:
5-amino-1-methylpyrimidine-2,4(1H,3H)-dione is used as a chemical intermediate for the synthesis of various drugs due to its versatile chemical structure and biological activity.
Used in Antiviral Applications:
5-amino-1-methylpyrimidine-2,4(1H,3H)-dione is used as an antiviral agent for its ability to inhibit viral replication and reduce the severity of viral infections.
Used in Antitumor Applications:
5-amino-1-methylpyrimidine-2,4(1H,3H)-dione is used as an antitumor agent for its potential to inhibit tumor growth and proliferation, offering a valuable contribution to cancer treatment.
Used in Anti-inflammatory Applications:
5-amino-1-methylpyrimidine-2,4(1H,3H)-dione is used as an anti-inflammatory agent to reduce inflammation and alleviate symptoms associated with inflammatory conditions.
Used in Pesticide Synthesis:
5-amino-1-methylpyrimidine-2,4(1H,3H)-dione is used as a key component in the development of pesticides, contributing to effective pest control solutions in agriculture.

Upstream product

• 6972-77-6 N-cyanoacetyl-N'-methyl-urea 
• 28495-88-7 1-methyl-5-nitrouracil 

Relevant academic research and scientific papers

Preparation method of theobromine

The invention discloses a preparation method of theobromine, and relates to the technical field of preparation of heterocyclic compounds containing purine ring systems. The method comprises the following steps: adding oxalyl chloride into cyanoacetic acid and a solvent at the temperature of -10-20 DEG C, concentrating to remove the solvent and oxalyl chloride after reaction, adding monomethylureaand the solvent at the temperature of 0-30 DEG C, adding alkali as an acid-binding agent, adding water after reaction, stirring, and filtering to obtain monomethyl cyanoacetylurea; adding water to dissolve cyanuric chloride, adding liquid caustic soda to adjust the pH value to 8-11, and reacting at 80-100 DEG C to generate methyl 4AU; dissolving monomethyl 4AU in formic acid, adding sodium nitrite, reacting at room temperature, adding a catalyst, keeping the temperature at 30-70 DEG C, recovering the catalyst after the reaction is finished, and concentrating mother liquor to recover formic acid, thereby obtaining monomethyl FAU; adding water and liquid caustic soda into monomethyl FAU, carrying out ring-closure reaction, and then adding acid to adjust to be neutral, so as to obtain 3-methyl xanthine; and carrying out a methylation reaction on 3-methylxanthine, and refining to obtain theobromine. The method has the advantages of few reaction steps, few side reactions, high yield and stable product quality.