239072-80-1

Upstream product

• 239072-79-8 tert-butyl 4-(4-cyanobenzyl)-3-oxopiperazine-1-carboxylate 

Downstream Products

• 239072-81-2 4-(6-chloronaphthalene-2-sulfonyl)-1-(4-cyanobenzyl)-2-piperazinone 
• 239073-80-4 1-(4-cyanobenzyl)-4-vinylsulfonyl-2-piperazinone 
• 239073-79-1 4-(7-chloro-2H-benzopyran-3-sulfonyl)-1-(4-cyanobenzyl)-2-piperazinone 
• 239073-82-6 4-chloromethylsulfonyl-1-(4-cyanobenzyl)-2-piperazinone 
• 239073-81-5 4-(5-chlorobenzofuran-2-sulfonyl)-1-(4-cyanobenzyl)-2-piperazinone 

Relevant academic research and scientific papers

METALLOENZYME INHIBITOR COMPOUNDS

The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.

Sulfonamide derivatives, processes for producing the same and utilization thereof

The present invention is to provide a compound or a salt thereof represented by the formula: wherein R1is an optionally substituted hydrocarbon group or an optionally substituted heterocyclic group, the ring A is an optionally substituted divalent nitrogen-containing heterocyclic group, X′ is an optionally substituted alkylene chain, Y is an optionally substituted divalent cyclic group, X is a chemical bond or an optionally substituted alkylene chain, and Z is (1) an optionally substituted amino group, (2) an optionally substituted imidoyl group or (3) an optionally substituted nitrogen-containing heterocyclic group, or a pro-drug thereof, which have activated coagulation factor X inhibitory activity and which are useful as anti-coagulants.