239080-31-0

Upstream product

• 239080-25-2 C₅₄H₆₄BrN₇O₁₃Si 
• 239080-23-0 C₅₄H₆₅N₇O₁₃Si 
• 239080-29-6 C₅₄H₅₆BrN₆O₁₀P 
• 239080-22-9 C₄₈H₅₁N₇O₁₃ 
• 239080-26-3 8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(tert-butyldimethylsilyl)oxy]methyl]cyclopentyl]-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine 
• 239080-28-5 8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-(hydroxymethyl)cyclopentyl]-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine 
• 239080-21-8 N-1-(2,4-dinitrophenyl)-5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine 
• 239080-20-7 5'-O-(monomethoxytrityl)-2',3'-O-isopropylideneinosine 
• 132342-52-0 ((3aR,4R,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)methanol 
• 5625-99-0 N,N'-diphenylphosphorodiamidic chloride 
• 67941-87-1 cyclohexylammonium S,S-diphenyl phosphorodithioate 
• 239080-30-9 8-bromo-N-1-[(1R,2S,3R,4R)-2,3-(isopropylidenedioxy)-4-[[(dianilinophosphoryl)oxy]methyl]cyclopentyl]-2',3'-O-isopropylideneinosine 

Relevant academic research and scientific papers

Alternative synthesis of cyclic IDP-carbocyclic ribose. Efficient cyclization of an 8-bromo-N1-[5-(phosphoryl)carbocyclic-ribosyl]inosine 5'- phenylthiophosphate derivative mediated by iodine

An efficient synthesis of cyclic IDP-carbocyclic-ribose, as a stable mimic for cyclic ADP-ribose, was achieved. N1-Carbocyclic-ribosylinosine derivative 15, prepared from N1(2,4-dinitrophenyl)inosine derivative 10 and an optically active carbocyclic amine 11, was converted to 8-bromo-N1- carbocyclic-ribosylinosine bis-phosphate derivative 20. Treatment of 20 with I2 in the presence of molecular sieves in pyridine gave the desired cyclic product 8 quantitatively, which was deprotected and reductively debrominated to give the target cyclic IDP-carbocyclic ribose (3).