239104-83-7Relevant academic research and scientific papers
Enzyme- and ruthenium-catalyzed dynamic kinetic resolution of functionalized cyclic allylic alcohols
Lihammar, Richard,Millet, Renaud,Baeckvall, Jan-E.
, p. 12114 - 12120 (2014/01/06)
Enantioselective synthesis of functionalized cyclic allylic alcohols via dynamic kinetic resolution has been developed. Cyclopentadienylruthenium catalysts were used for the racemization, and lipase PS-IM or CALB was employed for the resolution. By optimization of the reaction conditions the formation of the enone byproduct was minimized, making it possible to prepare a range of optically active functionalized allylic alcohols in good yields and high ee's.
Pt-catalyzed oxidative rearrangement of cyclic tertiary allylic alcohols to enones using aqueous hydrogen peroxide
Nagamine, Takashi,Kon, Yoshihiro,Sato, Kazuhiko
supporting information; experimental part, p. 744 - 746 (2012/09/22)
An oxidative rearrangement of cyclic tertiary allylic alcohols to β-disubstituted α,β-unsaturated ketones by Pt black catalyst with aqueous hydrogen peroxide is described. The reaction proceeds under organic solvent- and halide-free conditions and gives only water as a coproduct. The Pt black catalyst is commercially available and can be reused at least four times.
Photooxygenation of 3-aryl-2-cyclohexenols: Synthesis of a new series of antimalarial 1,2,4-trioxanes
Singh, Chandan,Gupta, Nitin,Puri, Sunil K.
, p. 205 - 207 (2007/10/03)
Using easily accessible 3-aryl-2-cyclohexenols, a photooxygenation route for the preparation of bicyclic 1,2,4-trioxanes is reported. Several of these trioxanes have shown significant antimalarial activity against multidrug resistant Plasmodium yoelii in
