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2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C, also known as 2-amino-4-(trifluoromethyl)thiazole-5-carbonitrile, is a chemical compound with the molecular formula C5H2F3N3S. It is a thiazole derivative featuring a trifluoromethyl group at the fourth position of the thiazole ring and an amino group at the second position. 2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C& is of significant interest in the fields of medicinal chemistry and pharmaceutical research due to its potential biological activities and therapeutic applications. It is recognized for its potential as a building block in the synthesis of various pharmaceuticals and agrochemicals, with ongoing research into its properties for possible pharmacological effects. The exploration of 2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C could pave the way for the development of new drugs and chemical agents with a range of pharmacological properties.

239135-55-8

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239135-55-8 Usage

Uses

Used in Pharmaceutical Research and Development:
2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C is used as a key intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of new drugs with diverse therapeutic profiles. Its unique structure allows for the exploration of various chemical modifications that could enhance pharmacological properties, such as potency, selectivity, and bioavailability.
Used in Agrochemical Synthesis:
In the agrochemical industry, 2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C is utilized as a building block for the creation of new agrochemicals. Its incorporation into these compounds can potentially lead to the development of more effective pesticides, herbicides, and other agricultural chemicals that are crucial for crop protection and yield enhancement.
Used in Medicinal Chemistry:
2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C is employed as a research tool in medicinal chemistry to investigate its potential pharmacological effects. 2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C&'s unique structural features make it a valuable candidate for studying its interactions with biological targets, which could lead to the discovery of new therapeutic agents for various diseases and conditions.
Used in Drug Discovery:
As a compound with potential biological activities, 2-AMINO-4-(TRIFLUOROMETHYL)THIAZOLE-5-C is used in drug discovery processes to identify and optimize lead compounds. Its properties are being investigated for their potential to treat a range of diseases, making it a promising candidate for further development into effective therapeutic agents.

Check Digit Verification of cas no

The CAS Registry Mumber 239135-55-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,3,9,1,3 and 5 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 239135-55:
(8*2)+(7*3)+(6*9)+(5*1)+(4*3)+(3*5)+(2*5)+(1*5)=138
138 % 10 = 8
So 239135-55-8 is a valid CAS Registry Number.
InChI:InChI=1/C5H3F3N2O2S/c6-5(7,8)2-1(3(11)12)13-4(9)10-2/h(H2,9,10)(H,11,12)

239135-55-8 Well-known Company Product Price

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  • Aldrich

  • (646059)  2-Amino-4-(trifluoromethyl)thiazole-5-carboxylicacid  97%

  • 239135-55-8

  • 646059-1G

  • 1,133.73CNY

  • Detail
  • Aldrich

  • (646059)  2-Amino-4-(trifluoromethyl)thiazole-5-carboxylicacid  97%

  • 239135-55-8

  • 646059-5G

  • 4,511.52CNY

  • Detail

239135-55-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-amino-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid

1.2 Other means of identification

Product number -
Other names 2-Amino-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:239135-55-8 SDS

239135-55-8Relevant academic research and scientific papers

Synthesis and Fungicidal Activity of Novel 2-Heteroatomthiazole-based Carboxanilides

Liu, Aiping,Wang, Xiaoguang,Liu, Xingping,Li, Jianming,Chen, Haobin,Hu, Li,Yu, Wanqi,He, Lian,Liu, Weidong,Huang, Mingzhi

, p. 1625 - 1629 (2017)

A new series of 2-heteroatomthiazole-based carboxanilides (8) are prepared by reacting 2-heteroatomthiazole-based carboxylic acid chlorides with 2,6-dibromo-4-(trifluoromethoxy)aniline. The structures of all the newly synthesized compounds were supported by spectroscopic data NMR, MS, and elemental analysis, etc. Bioassay showed that the compounds exhibited potent fungicidal activities against Rhizoctonia solani, etc. Particularly, N-(2,6-dibromo-4-(trifluoromethoxy)phenyl)-2-methoxy-4-(trifluoromethyl)thiazole-5-carboxamide (8a-2) showed fungicidal potency which was comparable to that of Thifluzamide, the only commercialized thiazole carboxanilide fungicides of succinate dehydrogenase inhibitor (SDHI).

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