23945-50-8

Basic information

• Product Name: 2-THIOURACIL-5-CARBOXYLIC ACID
• Synonyms: 2-THIOURACIL-5-CARBOXYLIC ACID;5-CARBOXY-2-THIOURACIL;5-CARBOXY-4-HYDROXY-2-THIOPYRIMIDINE;1,2,3,4-tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylicaci;5-carboxy-2-thiouracil free acid;1,2,3,4-tetrahydro-4-oxo-2-thioxopyrimidine-5-carboxylic acid;2-Thiouracil-5-carboxylic acid, 5-Carboxy-4-hydroxy-2-thiopyrimidine;1,2,3,4-Tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarboxylic acid
• CAS NO: 23945-50-8
• Molecular Formula: C₅H₄N₂O₃S
• Molecular Weight: 172.16
• EINECS: 245-948-8
• Mol File: 23945-50-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 246-247 °C (decomp)
• Boiling Point: 461.2°Cat760mmHg
• Flash Point: 232.7°C
• Appearance: /
• Density: 1.74g/cm³
• Vapor Pressure: 2.65E-09mmHg at 25°C
• Refractive Index: 1.719
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• PKA: 4.84±0.20(Predicted)
• CAS DataBase Reference: 2-THIOURACIL-5-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-THIOURACIL-5-CARBOXYLIC ACID(23945-50-8)
• EPA Substance Registry System: 2-THIOURACIL-5-CARBOXYLIC ACID(23945-50-8)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 23945-50-8(Hazardous Substances Data)

Usage

Uses

5-Carboxy-2-thiouracil is a possible anti-tumor agent when part of a metal complex.

InChI:InChI=1/C5H4N2O3S/c8-3-2(4(9)10)1-6-5(11)7-3/h1H,(H,9,10)(H2,6,7,8,11)

Upstream product

• 38026-46-9 ethyl 4-oxo-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxilate 
• 38026-46-9 Ethyl 4-Hydroxy-2-mercaptopyrimidine-5-carboxylate 

Relevant articles and documents

Thiouracil derivatives and metal surface-treating agent comprising thereof

A thiouracil derivative represented by the following general formula (1) or (2) STR1 (wherein, R1 and R2 each are a hydrogen atom or an alkyl group, and at least one of R1 and R2 is a hydrogen atom, and R3 is a hydrogen atom, an alkyl group or a phenyl group, and R4 is a bivalent saturated hydrocarbon group having 2 to 12 carbon atoms, Z is --COO--, CH2 O-- or --C6 H4 --CH2 O--, and R5 is a hydrogen atom or a methyl group), and a metal surface-treating agent for bonding a metal, particularly a noble metal to a resin or the like in high adhesive strength and in high water resistance and high durability which contains the above thiouracil derivative and an organic solvent such as acetone or ethanol.

Borane Reduction of Uracil Derivatives

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