23954-67-8Relevant academic research and scientific papers
Synthesis and SAR of new 5-phenyl-3-ureido-1,5-benzodiazephines as cholecystokinin-B receptor antagonists
Ursini,Capelli,Carr,Cassarà,Corsi,Curcuruto,Curotto,Dal Cin,Davalli,Donati,Feriani,Finch,Finizia,Gaviraghi,Marien,Pentassuglia,Polinelli,Ratti,Reggiani,Tarzia,Tedesco,Tranquillini,Trist,Van Amsterdam
, p. 3596 - 3613 (2007/10/03)
A series of 5-phenyl-3-ureidobenzodiazepine-2,4-diones was synthesized and evaluated as cholecystokinin-B (CCK-B) receptor antagonists. Structure-activity relationship (SAR) studies revealed the importance of the N-1 substituent for potent and selective C
1,5-Benzodiazepine-2,4-diones
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, (2008/06/13)
This invention relates to substituted 1,5-benzodiazepines having the formula SPC1 Wherein R1 and R2 are hydrogen or substituents, R3 is hydrogen or substituents, R4 is methyl or aryl group, As well as the process of producing the same. The compounds of the invention are tranquillizing analgesic, antipyretic and anti-inflammatory agents.
