2396-23-8

Usage

Type of compound

brominated benzene derivative

Functional group

perfluorinated propyl group attached at the fourth position

Usage

a. Organic synthesis
b. Building block for fluorinated organic compounds
c. Solvent
d. Intermediate in pharmaceuticals, agrochemicals, and electronic materials production

Perfluorinated propyl group

enhances stability and resistance to chemical and thermal degradation

Industrial applications

various, due to its stability and resistance to degradation

Safety and environmental impact

production and use should be carefully monitored and managed to minimize environmental impact

Upstream product

• 2402-72-4 2-(4-bromophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol 
• 108-86-1 bromobenzene 
• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 146500-63-2 1-bromo-4-(perfluoroprop-1-en-2-yl)benzene 
• 722-92-9 2-(4-aminophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol 

Downstream Products

• 36029-66-0 1-Trifluor-1-p-perfluorpropylphenyl-2,2-diphenylethylen 
• 73790-07-5 ethyl α-oxo-4-(perfluoroisopropyl)benzeneacetate 
• 73790-12-2 α,α-difluoro-4-(perfluoroisopropyl)benzeneacetic acid 
• 73789-97-6 ethyl α,α-difluoro-4-(perfluoroisopropyl)benzeneacetate 
• 353273-22-0 1-(4-(perfluoropropan-2-yl)phenyl)ethanone 
• 51114-06-8 methyl 4-(perfluoropropan-2-yl)benzoate 

Relevant academic research and scientific papers

An I(I)/I(III) Catalysis Route to the Heptafluoroisopropyl Group: A Privileged Module in Contemporary Agrochemistry

The heptafluoroisopropyl group is emerging as a privileged chemotype in contemporary agrochemistry and features prominently in the current portfolio of leading insecticides. To reconcile the expansive potential of this module with the synthetic challenges

PYRROLIDINYL SULFONE RORGAMMA MODULATORS

Described are RORγ modulators of the formula (I), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein all substituents are defined herein. Also provided are pharmaceutical compositions comprising the same. Such compounds and compositions are useful in methods for modulating RORγ activity in a cell and methods for treating a subject suffering from a disease or disorder in which the subject would therapeutically benefit from modulation of RORγ activity, for example, autoimmune and/or inflammatory disorders.