23964-29-6

Basic information

• Product Name: 3,5-DICHLORO-4-HYDROXYBENZOHYDRAZIDE
• Synonyms: 3,5-DICHLORO-4-HYDROXYBENZOHYDRAZIDE;3,5-dichloro-4-hydroxybenzohydrazide(SALTDATA: FREE);3,5-Dichloro-4-hydroxybenzoic acid hydrazide;Benzoic acid, 3,5-dichloro-4-hydroxy-, hydrazide
• CAS NO: 23964-29-6
• Molecular Formula: C₇H₆Cl₂N₂O₂
• Molecular Weight: 221.04
• Mol File: 23964-29-6.mol
• Article Data: 7

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.586g/cm³
• Refractive Index: 1.644
• PKA: 5.68±0.25(Predicted)
• CAS DataBase Reference: 3,5-DICHLORO-4-HYDROXYBENZOHYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-DICHLORO-4-HYDROXYBENZOHYDRAZIDE(23964-29-6)
• EPA Substance Registry System: 3,5-DICHLORO-4-HYDROXYBENZOHYDRAZIDE(23964-29-6)

Safety Data

• Hazardous Substances Data: 23964-29-6(Hazardous Substances Data)

Usage

General Description

3,5-Dichloro-4-hydroxybenzohydrazide is a chemical compound with the molecular formula C7H5Cl2N2O2. It is commonly used as a pesticide and herbicide, as well as a precursor in the synthesis of pharmaceuticals and agrochemicals. 3,5-DICHLORO-4-HYDROXYBENZOHYDRAZIDE is effective in controlling a wide range of pests and weeds due to its ability to inhibit the activity of key enzymes involved in their growth and reproduction. It is also known for its low mammalian toxicity, making it a relatively safe option for agricultural and industrial applications. However, due to its potential environmental and health impacts, the use and disposal of 3,5-dichloro-4-hydroxybenzohydrazide should be carefully regulated and monitored.

InChI:InChI=1/C7H6Cl2N2O2/c8-4-1-3(7(13)11-10)2-5(9)6(4)12/h1-2,12H,10H2,(H,11,13)

Upstream product

• 17302-82-8 ethyl 3,5-dichloro-4-hydroxybenzoate 
• 3337-59-5 methyl 3,5-dichloro-4-hydroxybenzoate 

Downstream Products

• 1191397-31-5 (Z)-ethyl 2-amino-2-(2-(3,5-dichloro-4-hydroxybenzoyl)hydrazono)acetate 
• 1251921-56-8 ethyl 2-(2-(3,5-dichloro-4-hydroxybenzoyl)hydrazinyl)-2-oxoacetate 

Relevant articles and documents

Compounds, Compositions and Methods Comprising 4N-Substituted Triazole Derivatives

The present invention relates to compounds, compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Table 1 or 2 or encompassed by formula I) or compositions comprising these compounds, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.

Compounds, Compositions and Methods Comprising Triazole Derivatives

The present invention relates to compositions and methods for treating a disease in an animal, which disease is responsive to inhibiting of functional cystic fibrosis transmembrane conductance regulator (CFTR) polypeptide by administering to a mammal in need thereof an effective amount of a compound defined herein (including those compounds set forth in Tables 1-2 or encompassed by formulas I-II) or compositions thereof, thereby treating the disease. The present invention particularly, relates to a method of treating diarrhea and polycystic kidney disease.

Identification of alkylidene hydrazides as glucagon receptor antagonists

High throughput screening of our small molecule combinatorial library identified a class of benzoylnaphthalenehydrazones with modest affinity for the human glucagon receptor. Optimization of this initial hit through a series of targeted libraries and traditional medicinal chemistry led to ligands with nanomolar affinities. Pharmacological evaluation demonstrated that these ligands were competitive glucagon receptor antagonists. Intravenous administration of a representative benzoylnaphthalenehydrazone into rats attenuated glucagon-stimulated glucose levels.