239784-12-4Relevant academic research and scientific papers
Dichotomy in regioselective cross-coupling reactions of 6,8-dichloropurines with phenylboronic acid and methylmagnesium chloride: Synthesis of 6,8-di-substituted purines
Hocek, Michal,Hockova, Dana,Dvorakova, Hana
, p. 889 - 894 (2007/10/03)
Pd-catalyzed cross-coupling reaction of 6,8-dichloro-9-(tetrahydropyran-2- yl)purine with one equivalent of phenylboronic acid proceeded regioselectively to give 8-chloro-6-phenylpurine, while the analogous Fe-catalyzed reaction with methylmagnesium chlor
Regiochemistry in the Pd-mediated coupling between 6,8-dihalopurines and organometallic reagents
Nolsoe, Jens M. J.,Gundersen, Lise-Lotte,Rise, Frode
, p. 366 - 372 (2007/10/03)
The regiochemistry in the Pd-mediated coupling between 6,8-dihalopurines and organometallic reagents has been examined. When 6,8-dichloropurines were reacted, highly selective coupling in the purine 6-position was obtained and the regiochemical outcome wa
