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CAS

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23983-05-3

(2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one is a chemical compound with the molecular formula C17H10ClN3OS. It is a benzimidazole derivative that contains a thiazole ring. (2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one exhibits potential biological activities and has been studied for its potential as an antifungal and antibacterial agent. Its unique structure and properties make it a promising candidate for further research and development in the field of medicinal chemistry.

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  • Thiazolo[3,2-a]benzimidazol-3(2H)-one,2-[(2-chlorophenyl)methylene]-

    Cas No: 23983-05-3

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  • 23983-05-3 Structure

  • Basic information

    1. Product Name: (2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one
    2. Synonyms: (2Z)-2-(2-Chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one; 2-(2-Chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one; 2-[(2-chlorophenyl)methylene][1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one; Thiazolo[3,2-a]benzimidazol-3(2H)-one, 2-[(2-chlorophenyl)methylene]-, (2Z)-
    3. CAS NO:23983-05-3
    4. Molecular Formula: C16H9ClN2OS
    5. Molecular Weight: 312.7735
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 23983-05-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 524.8°C at 760 mmHg
    3. Flash Point: 271.2°C
    4. Appearance: N/A
    5. Density: 1.47g/cm3
    6. Vapor Pressure: 4.15E-11mmHg at 25°C
    7. Refractive Index: 1.746
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one(23983-05-3)
    12. EPA Substance Registry System: (2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one(23983-05-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 23983-05-3(Hazardous Substances Data)

23983-05-3 Usage

Uses

Used in Pharmaceutical Industry:
(2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one is used as a potential antifungal and antibacterial agent due to its demonstrated biological activities. Its unique structure and properties make it a promising candidate for the development of new drugs to combat resistant strains of fungi and bacteria.
Used in Medicinal Chemistry Research:
(2Z)-2-(2-chlorobenzylidene)[1,3]thiazolo[3,2-a]benzimidazol-3(2H)-one is used as a subject of research in medicinal chemistry to explore its pharmacological potential and understand its mechanism of action. Further studies are needed to fully comprehend its applications in various fields and to develop new therapeutic agents based on its structure and properties.

Check Digit Verification of cas no

The CAS Registry Mumber 23983-05-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,3,9,8 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 23983-05:
(7*2)+(6*3)+(5*9)+(4*8)+(3*3)+(2*0)+(1*5)=123
123 % 10 = 3
So 23983-05-3 is a valid CAS Registry Number.

23983-05-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2-chloro-benzylidene)-benzo[4,5]imidazo[2,1-b]thiazol-3-one

1.2 Other means of identification

Product number -
Other names 2-[1-(2-Chloro-phenyl)-meth-(E)-ylidene]-benzo[4,5]imidazo[2,1-b]thiazol-3-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:23983-05-3 SDS

23983-05-3Relevant articles and documents

Fused Thiazoles: Synthesis and Antifungal Activity of 2-Arylidenethiazoloimidazopyridin-3(2H)-ones, 2-Arylidenethiazolobenzimidazol-3(2H)-ones and 6-Arylidenethiazolo-s-triazol-5(6H)-ones

Prasad, A. R.,Rao, A. Narasimha,Ramalingam, T.,Sattur, P. B.

, p. 776 - 778 (2007/10/02)

One-pot synthesis of the title compounds (II, IV) starting from 2-mercapto-1H-imidazopyridines (I; X=N), 2-mercaptobenzimidazoles (I; X=CH) or 5-aryl-3-mercapto-1,2,4-triazoles (III) is described.These compounds have been screened for their antifungal activities.

Synthesis of New 2-Substituted Benzylidenethiazolobenzimidazol-3(2H)-ones and Their Biological Activity

Soni, Namita,Barthwal, J. P.,Gupta, T. K.,Bhalla, T. N.,Parmar, S. S.,Bhargava, K. P.

, p. 785 - 788 (2007/10/02)

2-Substituted benzylidenethiazolobenzimidazol-3(2H)-ones (I-XIV) have been synthesized and found to possess anticonvulsant activity (0-60percent).These compounds also inhibit rat brain monoamine oxidase (MAO) (33.70-98.30percent) and succinate dehydrogenase (SDH) (25.72-78.95percent) in vitro of concentrations 4E-4 M and 6E-4 M, respectively.Structure-activity relationship has been dicussed.

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