24011-03-8

Basic information

• Product Name: 3-methylisoquinoline-5,8-dione
• CAS NO: 24011-03-8
• Molecular Formula: C₁₀H₇NO₂
• Molecular Weight: 173.1681
• Mol File: 24011-03-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 361.5°C at 760 mmHg
• Flash Point: 176.2°C
• Density: 1.311g/cm³
• Vapor Pressure: 2.06E-05mmHg at 25°C
• Refractive Index: 1.61
• CAS DataBase Reference: 3-methylisoquinoline-5,8-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methylisoquinoline-5,8-dione(24011-03-8)
• EPA Substance Registry System: 3-methylisoquinoline-5,8-dione(24011-03-8)

Safety Data

• Hazardous Substances Data: 24011-03-8(Hazardous Substances Data)

Upstream product

• 90-02-8 salicylaldehyde 
• 215237-76-6 5-hydroxy-3-methylisoquinoline 
• 5896-17-3 2-(phenylmethoxy)benzaldehyde 

Downstream Products

• 73590-03-1 6-hydroxy-7,9-dimethoxy-3-methylbenzoisoquinoline-5,10-quinone 
• 4589-33-7 bostrycoidin 

Relevant articles and documents

Novel Total Synthesis of Mansouramycin B

A novel total synthesis of Mansouramycin B (1) was performed via 10 steps in 28% overall yield starting from the readily available and cheap salicylaldehyde. Two key steps of this total synthesis are noteworthy. The first one is base-promoted one-pot aerobic aromatization of N-tosyltetrahydroisoquinoline 6, the second one is oxidation of 5-hydroxy-3-methyl-isoquinoline 8 with iodobenzene diacetate [PhI(OAc)2].