240122-43-4

Upstream product

• 133435-77-5 (S)-4-((benzyloxy)methyl)dihydrofuran-2(3H)-one 
• 240122-41-2 4-benzyloxy-2-benzyloxymethyl-3-hydroxymethyl-N,N-dimethyl-butyramide 
• 192864-00-9 (3S,4S)-3,4-Bis-benzyloxymethyl-dihydro-furan-2-one 
• 240122-42-3 4-benzo[1,3]dioxol-5-yl-2,3-bis-benzyloxymethyl-4-hydroxy-N,N-dimethyl-butyramide 

Downstream Products

• 240122-44-5 5-[(2S,3S,4S,5R)-3,4-Bis-benzyloxymethyl-5-(3,4-dimethoxy-phenyl)-tetrahydro-furan-2-yl]-benzo[1,3]dioxole 
• 853750-34-2 (2R,3S,4S,5S)-2-(3,4-dimethoxyphenyl)-3,4-bis(hydroxymethyl)-5-(3,4-methylenedioxyphenyl)tetrahydrofuran 

Relevant academic research and scientific papers

First total synthesis of tetrasubstituted tetrahydrofuran lignan, (-)- virgatusin

The first asymmetric total synthesis of (-)-virgatusin, a new furanolignan, isolated from phyllanthus virgatus, was accomplished in a stereoselective manner by nucleophilic addition of organolithium reagent to the functionalized lactone elaborated from di