24031-44-5

Upstream product

• 139714-07-1 3-Cyanomethyl-[4'-methoxy]-benzophenone 
• 151-50-8 potassium cyanide 
• 1711-11-1 3-cyanobenzoyl chloride 

Relevant academic research and scientific papers

Substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid compounds

There are disclosed substituted benzoylbenzene-, biphenyl- and 2-oxazole- alkanoic acid derivatives and the pharmacologically acceptable salts thereof as inhibitors of PLA2 and lipoxygenase, and their use in the treatment of inflammatory condit

Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives as inhibitors of pla2 and lipoxygenase

There are disclosed compounds of the formula wherein A is a group having the formula STR1 wherein X is --N-- or STR2 Z is STR3 R1 is hydrogen, lower alkyl or phenyl; R2 is hydrogen or lower alkyl; or R1 and R2 taken together form a benzene ring, with the proviso that when X is --N--, Z is other than STR4 R3 is hydrogen or lower alkyl; n is 1-2; B is STR5 wherein Y is OR5 or N(OH)R8 ; R4 and R5 are each, independently, hydrogen or lower alkyl; R6 is hydrogen, halo or nitro; R7 is STR6 R8 is lower alkyl; m is 0-3; and the pharmacologically acceptable salts thereof, and their use in the treatment of inflammatory conditions, such as rheumatoid arthritis, ulcerative colitis, psoriasis and other immediate hypersensitivity reactions; in the treatment of leukotriene-mediated naso-bronchial obstructive air-passageway conditions, such as allergic rhinitis, allergic bronchial asthma and the like; and as gastric cytoprotective agents.

Substituted benzoylbenzene-, biphenyl- and 2-oxazole-alkanoic acid derivatives

There are disclosed compounds of the formula wherein A is STR1 n is 1-2; B is STR2 wherein R4 and R5 are each, independently, hydrogen or lower alkyl; R6 is hydrogen, halo or nitro; STR3 R8 is lower alkyl; m is

Benzoylphenylacetic acid derivatives with antiinflammatory and analgesic activities

Several derivatives of m benzoylphenylacetic acid showed interesting antiinflammatory and analgesic properties associated with good gastric tolerance.