240401-25-6

Basic information

• Product Name: 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride
• Synonyms: 4-HYDROXY-4-HYDROXYMETHYLPIPERIDINE HCL
• CAS NO: 240401-25-6
• Molecular Formula: C₆H₁₃NO₂*ClH
• Molecular Weight: 167.63386
• Mol File: 240401-25-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride(240401-25-6)
• EPA Substance Registry System: 4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride(240401-25-6)

Safety Data

• Hazardous Substances Data: 240401-25-6(Hazardous Substances Data)

Usage

General Description

4-Hydroxy-4-hydroxyMethylpiperidine hydrochloride is a chemical compound comprised of piperidine, a common organic hexagonal ring structure largely utilised in the synthesis of pharmaceuticals, two hydroxyl groups and hydrochloride. As per available data, it is mostly used as an intermediate in organic synthesis and in drug production. Specific safety data and all of its uses are not readily available, indicating that it might be a less common or specialised substance. Extra caution should be taken to handle it till a comprehensive toxicological profile is established. Currently, its physical and chemical properties such as boiling point, melting point, density and molecular weight are also not universally available.

Upstream product

• 92197-36-9 4-hydroxy-4-(hydroxymethyl)-1-(phenylmethyl)piperidine 

Downstream Products

• 1239360-35-0 (S)-1-{2-[1-(4-fluorophenyl)indolylethylamino]-6-(aminopyrazine-2-ylamino)pyrimidinecarboxylic-4-yl}-4-(hydroxymethyl)-4-ol 
• 1239360-42-9 (S)-8-{2-[1-(4-fluorophenyl)ethyl]-6-(pyrazin-2-ylamino)pyrimidin-4-yl}-1,3-dioxo-8-azaspiro[4.5]decane-2-one 

Relevant articles and documents

Therapeutic agent pcnsl (by machine translation)

The present invention provides a malignant lymphoma therapeutic or preventive agent that comprises as the active ingredient a compound represented by general formula [1] as defined by (I) or (II), or a pharmaceutically acceptable salt thereof. [1] (I) X is CH or N; R1 is a halogen; R2 is a halogen, H, a cyano, a group represented by general formula [9], [9] an optionally substituted heteroaryl, or the like; R3 is H or a hydroxyl; R4 is H or an alkyl; and R5 is H or an alkyl. (II) X is -CRA, RA is -CORB, RB is an optionally substituted amino, alkoxy, or saturated cyclic amino group; R1 is a halogen; R2 is H; R3is H or a hydroxy; R4 is H or an alkyl; and R5 is H or an alkyl.

Phthalazine derivatives and remedies for erectile dysfunction

The present invention provides a phthalazine compound as a therapeutic agent for erectile dysfunction represented by the following formula, a pharmacologically acceptable salt thereof or a hydrate thereof: wherein R1and R2are the same as or different from each other and represent a halogen atom, a C1 to C4 alkyl group which may be substituted with a halogen atom, a C1 to C4 alkoxy group which may be substituted with a halogen atom or a cyano group; X represents a cyano group, a nitro group, a halogen atom, a hydroxyimino group which may be substituted or a heteroaryl group which may be substituted; Y represents a heteroaryl group, an aryl group which may be substituted, an alkynyl group which may substituted, an alkenyl group, an alkyl group, an optionally substituted saturated or unsaturated 4- to 8-membered amine ring, and the cyclic amine compound is a monocyclic compound, bicyclic compound or a spiro compound; l is an integer of 1 to 3; provided that the case where l is 1 or 2, X is a cyano group, a nitro group or a chlorine atom, R1is a chlorine atom, R2is a methoxy group and Y is a 5- or 6-membered amine ring substituted with a hydroxyl group is excluded.