240405-20-3 Usage
Description
2,3-dinor-11β-Prostaglandin F2α (2,3-dinor-11β-PGF2α) is a metabolite of PGD2 . Urinary excretion of 2,3-dinor-11β-PGF2α is increased in patients with mast cell activation disease (MCAD) and has been used as a marker of increased PGD2 levels. 2,3-dinor-11 β-PGF2α levels are also increased in the urine of patients with asthma and are positively correlated with impaired lung function.
Check Digit Verification of cas no
The CAS Registry Mumber 240405-20-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,4,0,4,0 and 5 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 240405-20:
(8*2)+(7*4)+(6*0)+(5*4)+(4*0)+(3*5)+(2*2)+(1*0)=83
83 % 10 = 3
So 240405-20-3 is a valid CAS Registry Number.
240405-20-3Relevant articles and documents
iPF2α-III metabolism. First total synthesis of 2,3-dinor iPF2α-III, a primary β-oxidation metabolite
Kim, Seongjin,Jung, Young-Ju,Lawson, John A,FitzGerald, Garret A,Rokach, Joshua
, p. 8277 - 8280 (2001)
The total synthesis of a primary iPF2α-III metabolite, namely dinor iPF2α-III 8, is described. The successful synthesis was finally accomplished by generating the carboxylic acid group at the end of the synthesis so as to avoid formation of an α,β-unsaturated carboxylic acid, which is prone to undergo side reactions.
