24048-40-6

Usage

Uses

Used in Organic Chemistry:
(1aS,8aS)-1,1aα,2,4a,5,6,7,8-Octahydro-4aβ,8,8-trimethyl-2-methylenecyclopropa[d]naphthalene is used as a key intermediate in organic chemistry for the synthesis of complex organic molecules. Its unique structure and reactivity make it a valuable component in creating novel compounds with specific properties.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1aS,8aS)-1,1aα,2,4a,5,6,7,8-Octahydro-4aβ,8,8-trimethyl-2-methylenecyclopropa[d]naphthalene is used as a building block for the development of new drugs. Its potential applications in drug discovery are attributed to its distinctive molecular architecture, which can be leveraged to design and synthesize pharmaceutically relevant molecules with improved efficacy and selectivity.
Used in Materials Science:
(1aS,8aS)-1,1aα,2,4a,5,6,7,8-Octahydro-4aβ,8,8-trimethyl-2-methylenecyclopropa[d]naphthalene also finds applications in materials science, where it can be employed in the development of new materials with unique properties. Its incorporation into material frameworks can lead to advancements in areas such as polymer science, nanotechnology, and material coatings.

Upstream product

• 83849-28-9 2-((1aS,4aR,8aR)-4a,8,8-Trimethyl-1,1a,4,4a,5,6,7,8-octahydro-cyclopropa[d]naphthalen-2-ylmethoxy)-cyclohepta-2,4,6-trienone 
• 83849-29-0 3,5,7-Trimethyl-2-((1aR,4aS,8aS)-4a,8,8-trimethyl-1,1a,4,4a,5,6,7,8-octahydro-cyclopropa[d]naphthalen-2-ylmethoxy)-cyclohepta-2,4,6-trienone 
• 470-40-6 cis-thujopsene 
• 472-66-2 (2,6,6-trimethyl-1-cyclohexen-1-yl)acetaldehyde 
• 917-54-4 methyllithium 
• 4677-90-1 (+/-)-Mayuron 
• 470-40-6 thujopsene 
• 4677-90-1 (+)-mayurone 
• 74-88-4 methyl iodide 
• 26341-59-3 Δ³-thujopsen-2α-ol 
• 62861-94-3 (1,3,3-Trimethyl-2-methylen-1-cyclohexenyl)acetylchlorid 
• 62861-97-6 1-Diazo-4-(1,3,3-trimethyl-2-methylene-cyclohexyl)-butan-2-one 
• 62861-95-4 1-Diazo-3-(1,3,3-trimethyl-2-methylene-cyclohexyl)-propan-2-one 
• 62861-96-5 3-(1,3,3-Trimethyl-2-methylene-cyclohexyl)-propionic acid methyl ester 

Relevant academic research and scientific papers

Terpenoids. IX. Permanganate Oxidation of Thujopsene. 2. Neutral Products

Permanganate oxidation of thujopsene 1 in dry and aqueous acetone was reexamined with a careful separation of the neutral part of the products.In dry acetone, the major products were Δ9-thujopsen-8β- and 8α-ols (2 and 3) which easily decomposed to thujopsadiene 6.In aqueous acetone, 1 gave 8β-hydroxythujopsan-9-one 8 and thujopsane-8α,9α-diol 11 as main products, besides 8β,9β-diol 10, 8α-hydroxythujopsan-9-one 9, and epimeric allyl alcohols 2 and 3.The hydroxy ketone 8 was isomerized to a ring contracted compound, 4α-acetyl-4β-hydroxy-6α,10,10-trimethyltricyclo1,3>decane 4 during alumina chromatography. 8β,9-Epoxy-10-thujopsanone 5 was isolated as a minor product.Kawamura's glycol was an eutectic mixture of 10 and 11.

DICYANOANTHRACENE-SENSITIZED PHOTOOXYGENATION OF THUJOPSENE

9,10-Dicyanoanthracene-sensitized photooxygenation of thujopsene proceeded by singlet oxygen, but the reaction with added biphenyl caused an electron transfer and produced a novel product which has no longer possessed the cyclopropane ring.The ring cleavage is best explained in terms of intermediary formation of a radical cation.

PYROLYSIS OF 2-ALLYLOXYTROPONES: A NEW ELIMINATION RECTION TO TERMINAL DIENES

By pyrolysis over 140 deg C, several 2-alkenyloxytropones gave terminal dienes and regenerated tropolones.The elimination proceeded in the electrocyclic 6?+2?+2?-mode on the Claisen intermediates.This was applied to a synthesis of thujopsadiene.