240485-10-3Relevant academic research and scientific papers
Enantioselective synthesis of alkyl-substituted eight-membered lactones by Claisen rearrangement
Harrison, Justin R.,Holmes, Andrew B.,Collins, Ian
, p. 972 - 974 (2007/10/03)
The Claisen rearrangement of alkenyl-substituted ketene acetals (produced in situ by selenoxide elimination from the corresponding phenylselenoacetaldehyde-derived acetals of enantiomerically pure 1,3-diol derivatives) afforded unsaturated eight-membered lactones with control of stereochemistry of methyl substituents at C-4, C-5 and C-7, as well as a fused system.
