24060-74-0Relevant academic research and scientific papers
Synthesis and evaluation of unsymmetrical heterocyclic thioureas as potent β-glucuronidase inhibitors
Taha, Muhammad,Ismail, Nor Hadiani,Jamil, Waqas,Khan, Khalid Mohammed,Salar, Uzma,Kashif, Syed Muhammad,Rahim, Fazal,Latif, Yawar
, p. 3166 - 3173 (2015)
Thiourea analogs 1-20 were synthesized and evaluated for their in vitro β-glucuronidase inhibitory potential. The compounds 9 (0.86 ± 0.01 μM), 6 (1.24 ± 0.01 μM), 16 (1.64 ± 0.02 μM) and 15 (2.12 ± 0.02 μM) showed potent activity. Other analogs 1-5, 7, 8
