24067-13-8

Upstream product

• 585-79-5 m-nitrobromobenzene 
• 420-04-2 CYANAMID 
• 99-09-2 3-nitro-aniline 
• 1627898-19-4 4,6-dimethoxy-2-[(3-nitrophenyl)amino]pyrimidine 

Downstream Products

• 4431-64-5 3-guanidinobenzenesulfonamide 
• 1421340-52-4 C₂₀H₁₆N₆O₂S 
• 1421693-55-1 C₁₆H₁₃F₃N₆O₂S 
• 1189558-95-9 4-(4-methyl-2-(methylamino)thiazol-5-yl)-2-(3-nitrophenylamino)pyrimidine-5-carbonitrile 

Relevant academic research and scientific papers

Benzene guanidine containing strong electron withdrawing group and preparation method of salt thereof

The invention discloses a benzene guanidine containing strong electron withdrawing group and preparation method of salt thereof. The benzene guanidine and the salt compound of the benzene guanidine can be applied as the accelerator of rubber, medicine int

Cleavage of 2-(Arylamino)-4,6-dimethoxypyrimidines to yield arylguanidines

A novel method for the synthesis of aryl-substituted guanidines in good overall yields is presented; it consists of the acidic cleavage of 2-(arylamino)-4,6-dimethoxypyrimidines, which were prepared by coupling aryl bromides with 2-amino-4,6-dimethoxypyrimidine. This methodology introduces a new means of protection for the guanidine functionality. Copyright

PYRADAZINE COMPOUNDS AS GSK-3 INHIBITORS

The present invention relates generally to inhibitors of the kinases, such as GSK3, and more particularly to fused pyradazine compounds according to formula (I) and methods of their use.

Compositions and methods for inhibiting arginase activity

Compositions and methods for inhibiting arginase activity, including arginase activity in a mammal, are provided. Methods of making the compositions of the invention are also provided as are methods of using the compositions therapeutically. The compositions described herein are useful for alleviating or inhibiting a variety of arinase- and NO synthase-related disorders, including heart diseae, gastrointestinal motility disorders, and penile erectile dysfunction in humans.