240805-41-8Relevant academic research and scientific papers
Highly diastereoselective aziridination of α,β-unsaturated amides using diaziridine
Ishihara, Hiroyuki,Ito, Yoshio N.,Katsuki, Tsutomu
, p. 984 - 985 (2001)
Racemic 3-cyclohexyl-1-methyldiaziridine was found to react with α,β-unsaturated amides in basic conditions, giving N-unprotected trans-aziridines, while 3,3-pentamethylenediaziridine had been reported to afford cis-aziridines in high diastereoselectivity
Highly diastereo- and enantioselective aziridination of α,β-unsaturated amides with diaziridine and mechanistic consideration on its stereochemistry
Ishihara, Hiroyuki,Hori, Kiyoto,Sugihara, Hiroyasu,Ito, Yoshio N.,Katsuki, Tsutomu
, p. 4272 - 4286 (2007/10/03)
During studies of aziridination of α,β-unsaturated amides with diaziridine, we found that we could prepare both the cis- and trans-aziridinecarboxamides by choosing an appropriately substituted diaziridine. While 3-monosubstituted diaziridine 2 was suitab
