24082-42-6

Upstream product

• 4670-09-1 2-(3,5-dihydroxyphenyl)acetic acid 
• 95-01-2 2,4-Dihydroxybenzaldehyde 
• 1141854-11-6 2,4-bis(tert-butyldiphenylsilyloxy)benzaldehyde 
• 4721-07-7 oxyresveratrol 
• 141-97-9 ethyl acetoacetate 

Downstream Products

• 102752-22-7 2,4,3',5'-tetraacetoxy-bibenzyl 
• 80715-06-6 Ethandiyl-1-(3-benzyl-8-hydroxy-5-oxo-1,2,3,4-tetrahydro-5H-benzopyrano-<3,4-c>-9-pyridin)-2-(3-benzyl-10-hydroxy-5-oxo-1,2,3,4-tetrahydro-5H-benzopyrano-<3,4-c>-8-pyridin) 
• 80715-08-8 Ethandiyl-1-(3-benzyl-8-methoxy-5,5-dimethyl-1,2,3,4-tetrahydro-5H-benzopyrano-<3,4-c>-9-pyridin)-2-(3-benzyl-10-methoxy-5,5-dimethyl-1,2,3,4-tetrahydro-5H-benzopyrano-<3,4-c>-8-pyridin) 
• 24131-34-8 2,4,3',5'-tetramethoxy-bibenzyl 

Relevant academic research and scientific papers

Molecular design of potent, hydrophilic tyrosinase inhibitors based on the natural dihydrooxyresveratrol skeleton

In this study, dihydrooxyresveratrol glucosides 3–6 were synthesized for the first time to the best of our knowledge by the Wittig reaction and Schmidt glycosylation as key steps for the purpose of developing novel hydrophilic tyrosinase inhibitors. Resul

Synthetic method for natural product 2,3',4,5'-tetrahydroxy bibenzyl

The invention discloses a synthetic method for a natural product 2,3',4,5'-tetrahydroxy bibenzyl. The synthetic method comprises the following steps that 3,5-dyhydroxy phenylacetic acid and 2,4-dyhydroxy benzaldehyde serve as materials and conduct a condensation reaction in the presence of alkali to obtain 3-(3,5-dyhydroxy phenyl)-7-hydroxy coumarin; then a ring opening decarboxylation reaction is conducted under an alkaline condition, and E-2,3',4,5'-tetrahydroxy toluylene is obtained; and finally a hydrogenation reaction is conducted to obtain the natural product 2,3',4,5'-tetrahydroxy bibenzyl. According to the synthetic method, the materials are easy to obtain, the reaction route is simple, atom economy is high, post-treatment is succinct, and productivity is high.

Identification of dihydrostilbenes in Pholidota chinensis as a new scaffold for GABAA receptor modulators

A dichloromethane extract of stems and roots of Pholidota chinensis (Orchidaceae) enhanced GABA-induced chloride currents (IGABA) by 132.75 ± 36.69% when tested at 100 μg/mL in a two-microelectrode voltage clamp assay, on Xenopus laevis oocytes

Chemical transformations of oxyresveratrol (trans-2,4,3′,5′-tetrahydroxystilbene) into a potent tyrosinase inhibitor and a strong cytotoxic agent

From oxyresveratrol (trans-2,4,3′,5′-tetrahydroxystilbene 1), seven derivatives were prepared, including trans-2-methoxy-4,3′,5′-trihydroxystilbene (2), trans-2,3′-dimethoxy-4,5′-dihydroxystilbene (3), trans-4,3′-dimethoxy-2,5′-dihydroxystilbene (4), tran