24085-34-5

Basic information

• Product Name: methyl 5-(2-bromoacetyl)-2-methoxybenzoate
• Synonyms: methyl 5-(2-bromoacetyl)-2-methoxybenzoate
• CAS NO: 24085-34-5
• Molecular Formula: C11H11BrO4
• Molecular Weight: 287.11
• Mol File: 24085-34-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 153-154 °C
• Boiling Point: 404.2±35.0 °C(Predicted)
• Density: 1.464±0.06 g/cm3(Predicted)
• CAS DataBase Reference: methyl 5-(2-bromoacetyl)-2-methoxybenzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-(2-bromoacetyl)-2-methoxybenzoate(24085-34-5)
• EPA Substance Registry System: methyl 5-(2-bromoacetyl)-2-methoxybenzoate(24085-34-5)

Safety Data

• Hazardous Substances Data: 24085-34-5(Hazardous Substances Data)

Upstream product

• 16475-90-4 estere metilico dell'acido 5-acetilsalicilico 
• 39971-36-3 5-acetyl-2-methoxybenzoic acid methyl ester 

Downstream Products

• 802604-14-4 5-[2-(Benzyl-tert-butyl-amino)-acetyl]-2-methoxy-benzoic acid methyl ester 
• 1373428-09-1 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(methoxy)benzoic acid 
• 1373428-00-2 methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(methoxy)benzoate 
• 376387-65-4 (S)-N-[2-(3-Quinolylmethanesulfonyl)-1-(3-methoxycarbonyl-4-methoxyphenyl)ethyl]-N-hydroxyformamide 
• 802884-57-7 2-(Benzyl-tert-butyl-amino)-1-(3-hydroxymethyl-4-methoxy-phenyl)-ethanol 

Relevant articles and documents

Synthesis and bioactivity of substituted benzoylguanidine derivatives as potent Na+/H+ exchanger inhibitors

A novel series of substituted benzoylguanidine derivatives were designed and synthesized in order to evaluate their NHE1 inhibitory activity. Most of them were found to inhibit NHE1-mediated platelet swelling in a concentration-dependent manner, and eight compounds showed more potent NHE1 inhibitory activity than Cariporide. Compound 6f with an IC50 value of 1.08 × 10-10 molmiddot;L-1, was 39 times more potent than lead compound CPU-X-050420 in vitro tests. A novel series of 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)benzoylguanidine derivatives 6a-6i have been synthesized and screened for their NHE1 inhibitory activity. Copyright

Pharmaceutically active bicyclic-heterocyclic amines

The pharmaceutically active bicyclic heterocyclic amines (XXX) STR1 where W1 is --N= or --CH=; W3 is --N= or --CH=; W5 is --N= or --CR5 -- with the proviso that W5 is --CR5 -- when both W1 and W3 are --N= which are useful as pharmaceuticals in treating mild and/or moderate to severe head injury, subarachnoid hemorrhage and subsequent ischemic stroke, asthma and reduction of mucous formation/secretion in the lung and other diseases and injuries.

NOVEL ANTIHYPERTENSIVE AGENT

This invention is to the compound 5-2-3-(1,3-benzodioxol-5-yl)-1-methylpropyl!amino!-1-hydroxyethyl!-2-methoxyben zamide having the formula, STR1 pharmaceutically acceptable salts and individual optical isomers thereof, pharmaceutical compositions comprising as the active ingredient the compound of Formula 1 or salts or isomers thereof and the use of said compound, or salt or isomer thereof or pharmaceutical composition comprising same in the treatment of hypertension.