241161-18-2

Basic information

• Product Name: (+/-)-N-(2,6-dinitrophenyl)glutamic acid
• CAS NO: 241161-18-2
• Molecular Weight: 313.224
• Mol File: 241161-18-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (+/-)-N-(2,6-dinitrophenyl)glutamic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)-N-(2,6-dinitrophenyl)glutamic acid(241161-18-2)
• EPA Substance Registry System: (+/-)-N-(2,6-dinitrophenyl)glutamic acid(241161-18-2)

Safety Data

• Hazardous Substances Data: 241161-18-2(Hazardous Substances Data)

Upstream product

• 617-65-2 Glutamic acid 
• 606-21-3 1-chloro-2,6-dinitrobenzene 

Relevant articles and documents

Synthesis, glycine/NMDA and AMPA binding activity of some new 2,5,6- trioxopyrazino[1,2,3-de]quinoxalines and of their restricted analogs 2,5- dioxo- and 4,5-dioxoimidazo[1,5,4-de]quinoxalines

The synthesis of some new 1,2,3,5,6,7-hexahydro-2,5,6- trioxopyrazino[1,2,3-de]quinoxalines 1c-g and of their restricted analogs 2,4,5,6-tetrahydro-2,5-dioxo-1H- 2a-g and 5,6-dihydro-4,5-dioxo-4H- imidazo[1,5,4-de]quinoxalines 3a-d is reported. Compounds 1c-g, 2a-g, and 3a- d were tested for their binding activity at the glycine/NMDA and AMPA receptors. The results show that only the 6,6,6-tricyclic derivatives 1c-g are able to bind to the glycine/NMDA and AMPA receptors, although with lower affinity than the previously reported lead compounds 1a-b. In contrast, the 5,6,6-tricyclic derivatives 2a-g are inactive at both receptors and only one 4,5-dioxoimidazoquinoxaline (3b) displays a weak glycine/NMDA receptor affinity.