24122-28-9Relevant academic research and scientific papers
Nafion-H: An efficient and recyclable heterogeneous catalyst for the one-pot synthesis of 2,3-disubstituted 4-(3H)-quinazolinones under solvent-free microwave irradiation conditions
Lingaiah, B. Venkat,Ezikiel,Yakaiah,Reddy, G. Venkat,Shanthan Rao
, p. 2507 - 2509 (2006)
A one-pot synthesis of 2,3-disubstituted 4-(3H)-quinazolinones has been carried out efficiently by the three-component coupling of isatoic anhydride/anthranilic acid, orthoesters, and amines in the presence of Nafion-H (a perfluorinated resin-supported su
Copper-catalyzed radical methylation/C-H amination/oxidation cascade for the synthesis of quinazolinones
Bao, Yajie,Yan, Yizhe,Xu, Kun,Su, Jihu,Zha, Zhenggen,Wang, Zhiyong
, p. 4736 - 4742 (2015/05/13)
A copper-catalyzed radical methylation/sp3 C-H amination/oxidation reaction for the facile synthesis of quinazolinone was developed. In this cascade reaction, dicumyl peroxide acts not only as a useful oxidant but also as an efficient methyl source. Notably, a methyl radical, generated from peroxide, was confirmed by electron paramagnetic resonance for the first time.
