24127-05-7Relevant articles and documents
Endo-selective pd-catalyzed silyl methyl heck reaction
Parasram, Marvin,Iaroshenko, Viktor O.,Gevorgyan, Vladimir
, p. 17926 - 17929 (2014)
A palladium (Pd)-catalyzed endo-selective Heck reaction of iodomethylsilyl ethers of phenols and aliphatic alkenols has been developed. Mechanistic studies reveal that this silyl methyl Heck reaction operates via a hybrid Pd-radical process and that the silicon atom is crucial for the observed endo selectivity. The obtained allylic silyloxycycles were further oxidized into (Z)-alkenyldiols.