2413-01-6

Usage

Xanthene derivative

Yes

Hexahydro-9-(4-nitrophenyl) group attached

Yes

Characteristic structure

Determined by the hexahydro-9-(4-nitrophenyl) group

Commonly used in

Organic synthesis and pharmaceutical research

Potential pharmacological properties

Yes

Possible applications

Development of new drugs, medical research

Other uses

Dye or pigment in certain industries

Upstream product

• 504-02-9 1,3-cylohexanedione 
• 555-16-8 4-nitrobenzaldehdye 
• 323180-29-6 2,2'-((4-nitrophenyl)methylene)bis(3-hydroxycyclohex-2-en-1-one) 

Relevant academic research and scientific papers

Magnetic Fe–Cr–Ni oxide alloy nano-belts prepared from the chemical decomposition of a stainless steel screw (a top-down approach): an efficient and cheap catalyst for multicomponent reactions

Abstract: A new, cheap, and accessible method has been used for the preparation of nano-belts from the chemical decomposition (top-down approach) of a cheap stainless steel screw and found as an efficient magnetically recyclable nanocatalyst for the prepa

Natural phosphate as an efficient and green catalyst for synthesis of tetraketone and xanthene derivatives

Abstract: Natural phosphate was applied as an efficient and ecofriendly catalyst for the synthesis of tetraketones (2–2.5?h, 90–100?%) and xanthenes (6.5–8.5?h, 84–95?%) via Knoevenagel–Michael cascade reaction of aromatic aldehydes with 1,3-cyclic diketones in water and ethanol, respectively. This protocol provides several advantages over the traditional chemical synthesis, such as simple work-up, easy handling procedure, non-toxicity and stability of catalyst, low cost and environmental friendliness. Graphical Abstract: [Figure not available: see fulltext.]

Facile and rapid synthesis of diverse xanthene derivatives using lanthanum(III) chloride/chloroacetic acid as an efficient and reusable catalytic system under solvent-free conditions

LaCl3/ClCH2COOH was used as an efficient, and recyclable catalytic system for synthesis of 11H-benzo[a]xanthene-11-one, hexahydro-1H-xanthene- 1,8(2H)-dione and 11-aryl-10H-diindeno[1,2-b:2',1'-e]pyran-10,12(11H)- -dione derivatives

One-pot synthesis of pyran derivatives using silica-coated magnetic nanoparticles functionalized with piperidinium benzene-1,3-disulfonate as a new efficient reusable catalyst

Abstract: Fe3O4 nanoparticles were coated with silica followed by surface modification using a silylating agent and piperidine to obtain piperidinium benzene-1,3-disulfonate salt (PBDS) silica-coated magnetic nanoparticles (SCMNPs).

L-proline as an efficient asymmetric induction catalyst in the synthesis of chromeno[2,3-d]pyrimidine-triones, xanthenes in water

The multi-component reactions involving aromatic aldehydes, dimethylcyclohexane-1, 3-dione/cyclohexane-1, 3-dione and barbituric acids were carried out in presence of the organo catalyst L-proline in aqueous medium at ambient temperature. The reactions af

Method for preparation of 9-aryl-2, 3, 4, 5, 6, 7-hexahydro-2H-xanthene-1, 8-dione without catalyst

Belonging to the technical field of chemical material preparation, the invention provides a method for synthesis of 9-aryl-2, 3, 4, 5, 6, 7-hexahydro-2H-xanthene-1, 8-dione without catalyst. The method includes: carrying out condensation reaction on aroma

Nano-zirconia as an excellent nano support for immobilization of sulfonic acid: A new, efficient and highly recyclable heterogeneous solid acid nanocatalyst for multicomponent reactions

Nano-zirconia-supported sulfonic acid [nano-ZrO2-SO3H (n-ZrSA)] is synthesized by immobilizing sulfonic acid groups on the surface of nano zirconium dioxide to produce a novel heterogeneous reusable solid acid nanocatalyst. This new nanocatalyst is characterized by FT-IR spectroscopy, thermogravimetric analysis (TGA), X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), transmission electron microscopy (TEM), the Hammett acidity function and pH analysis. The introduced nano-zirconia-supported sulfonic acid is used as an efficient and recyclable catalyst for different heterocyclic multicomponent reactions such as the synthesis of hexahydroquinoline, 1,8-dioxo-decahydroacridine, polyhydroquinoline and 1,8-dioxo-octahydroxanthene derivatives. Optimization of the reaction conditions was studied using a central composite design (CCD) which is one of the most widely used response surface methodologies. The newly prepared heterogeneous solid acid nanocatalyst is easily separated and reusable for five cycles without any apparent loss of its catalytic activity, which confirmed the stability of the covalent bonding of the sulfonic acid groups. n-ZrSA has advantages such as its low cost, low toxicity, ease of preparation, good stability, high reusability and operational simplicity.

Efficient synthesis of xanthenedione derivatives using cesium salt of phosphotungstic acid as a heterogeneous and reusable catalyst in water

Cs2.5H0.5PW12O40has been reported to be an efficient catalyst for the synthesis of 1,8-dioxo-octahydroxanthene from aldehydes and 1,3-cyclohexanedione/dimedone in water. This approach is environmentally benign with clean synthetic procedure, short reaction time, easy workup procedure, excellent yield, and regeneration of catalyst, which made this protocol efficient and safe.

Facile synthesis and investigation of 1,8-dioxooctahydroxanthene derivatives as corrosion inhibitors for mild steel in hydrochloric acid solution

An environmentally friendly and facile method for the preparation of 1,8-dioxooctahydroxanthene between aldehydes with dimedone or cyclohexane-1,3-dione is presented in the presence of trichloromelamine (TCM) under solvent-free conditions. Also, for the f

Facile and efficient synthesis of xanthenedione derivatives promoted by niobium pentachloride

Xanthenedione derivatives were synthesised in one-pot reactions between arylaldehyde derivatives and 1, 3-cyclohexanedione promoted by niobium pentachloride. This new method is simple, cost-effective, high-yielding with a good variety of substrates genera