24134-26-7

Usage

Uses

Used in Pharmaceutical Industry:
1H-Imidazo[1,2-a]benzimidazole,2,3-dihydro-(8CI,9CI) is used as a potential pharmaceutical compound for its unique structure and properties. Its heterocyclic nature may contribute to the development of new drugs with specific therapeutic effects.
Used in Agrochemical Industry:
In the agrochemical industry, 1H-Imidazo[1,2-a]benzimidazole,2,3-dihydro-(8CI,9CI) may be utilized as a precursor or active ingredient in the development of new pesticides or herbicides, leveraging its chemical properties to target specific pests or weeds.
Used in Material Science:
1H-Imidazo[1,2-a]benzimidazole,2,3-dihydro-(8CI,9CI) can be employed in material science for the synthesis of new materials with unique properties. Its heterocyclic structure may contribute to the development of advanced materials with applications in various fields, such as electronics, optics, or nanotechnology.

InChI:InChI=1/C9H9N3/c1-2-4-8-7(3-1)11-9-10-5-6-12(8)9/h1-4H,5-6H2,(H,10,11)

Upstream product

• 130838-45-8 1-(4,5-dihydro-1H-imidazol-2-yl)benzotriazole 
• 84797-54-6 (1H-Benzoimidazol-2-yl)-(2-chloro-ethyl)-amine 
• 151-56-4 ethyleneimine 
• 5709-67-1 2-Nitrobenzimidazole 

Downstream Products

• 1574315-81-3 2-(2,3-dihydro-9H-imidazo[1,2-a]benzimidazol-9-yl)-N'-(2-hydroxy-3,5-dinitrobenzylidene)acetohydrazide 

Relevant academic research and scientific papers

Reactions of N-aryl-N-(4,5-dihydro-1H-imidazol-2-yl) hydroxylamines with methanesulfonyl chloride. Synthesis and acylation of 2,3-dihydro-1H-imidazo [1,2-a]benzimidazoles

Reactions of N-aryl-N-(4,5-dihydro-1H-imidazo-2-yl)-hydroxylamines 1a-d with methanesulfonyl chloride in the presence of triethylamine afforded 2,3-dihydroimidazo[1,2-a]benzimidazoles 2a-d. The latter compounds treated with acetic anhydride, methane or phenylsulfonyl chlorides gave N-1 acetyl or N-1 methane or phenylsulfonyl derivatives 3a-d and 4a-b, respectively.

The Photolysis of 1-(4,5-Dihydro-1H-imidazol-2-yl)benzotriazole

1-(4,5-Dihydro-1H-imidazolo-2-yl)benzotriazole was photolyzed at 254 nm yielding 1,2-dihydro-4H-imidazobenzimidazole.

Potential radiosensitizing agents. 5. 2-Substituted benzimidazole derivatives

A series of 2-substituted benzimidazoles and their derivatives have been synthesized and tested for their ability to selectively sensitize hypoxic Chinese hamster cells (V-79) toward the lethal effect of ionizing radiation. These compounds were prepared by reacting the 2-substituted benzimidazoles with 1,2-epoxy-3-methoxypropane in the presence of potassium carbonate. Reaction of the 2-nitro and 2-methylsulfonyl analogue with the epoxide also yielded a cyclized material, which was confirmed to be a benzimidazo[2,1-b]oxazole. In an attempt to increase the electron affinity, 5- or 6-nitro-2-substituted-benzimidazoles were also synthesized and then reacted with the epoxide to yield the corresponding 1-substituted derivatives. The results of the biological tests for the radiosensitizing activity of these agents against Chinese hamster cells (V-79) in culture indicated the 2-nitro-substituted analogues were the most effective sensitizers in this series.