2416-25-3Relevant academic research and scientific papers
Method for synthesizing 3-substituted aminobenzo [c] isothiazole derivative
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Paragraph 0071-0072; 0074-0076, (2020/12/29)
The invention provides a method for synthesizing a 3-substituted aminobenzo [c] isothiazole derivative, which comprises the following steps: by using an amide N-substituted benzamide compound as an initial raw material, carrying out carbonyl oxygen sulfur replacement reaction and cyclization reaction to obtain the 3-substituted aminobenzo [c] isothiazole derivative. According to the method for synthesizing the 3-substituted aminobenzo [c] isothiazole derivative, the whole synthesis route is short in step, good in repeatability, mild in operation condition and high in safety, large-scale production and industrial popularization are facilitated, application of green and environment-friendly industrial production is facilitated, and wide application prospects are achieved.
