24192-87-8Relevant academic research and scientific papers
Enhancing excited state intramolecular proton transfer in 2-(2′-hydroxyphenyl)benzimidazole and its nitrogen-substituted analogues by β-cyclodextrin: The effect of nitrogen substitution
Chipem, Francis A. S.,Behera, Santosh Kumar,Krishnamoorthy
, p. 4084 - 4095 (2013)
Excited state intramolecular proton transfer (ESIPT) in nitrogen-substituted analogues of 2-(2′-hydroxyphenyl)benzimidazole (HPBI), 2-(2′-hydroxyphenyl)-3H-imidazo[4,5-b]pyridine (HPIP-b), and 2-(2′-hydroxyphenyl)-3H-imidazo[4,5-c]pyridine (HPIP-c) have b
Photoinduced proton and charge transfer in 2-(2′-hydroxyphenyl) imidazo[4,5-b]pyridine
Brenlla, Alfonso,Veiga, Manoel,Pérez Lustres, J. Luis,Ríos Rodríguez, M. Carmen,Rodríguez-Prieto, Flor,Mosquera, Manuel
, p. 884 - 896 (2013)
This paper deals with the interplay between solvent properties and isomerism of 2-(2′-hydroxyphenyl)imidazo[4,5-b]pyridine (1), and the proton and charge-transfer processes that the different isomers undergo in the first-excited singlet state. We demonstr
Photoinduced proton and charge transfer in 2-(2a?2-Hydroxyphenyl) imidazo[4,5-b ]pyridine
Brenlla, Alfonso,Veiga, Manoel,Peì?rez Lustres, J. Luis,Riì?os Rodriì?guez, M. Carmen,Rodriì?guez-Prieto, Flor,Mosquera, Manuel
, p. 884 - 896 (2013/04/23)
This paper deals with the interplay between solvent properties and isomerism of 2-(2a?2-hydroxyphenyl)imidazo[4,5-b]pyridine (1), and the proton and charge-transfer processes that the different isomers undergo in the first-excited singlet state. We demons
Microwave-assisted one step high-throughput synthesis of benzimidazoles
Lin, Shou-Yuan,Isome, Yuko,Stewart, Ethan,Liu, Ji-Feng,Yohannes, Daniel,Yu, Libing
, p. 2883 - 2886 (2007/10/03)
One-pot synthesis of benzimidazoles from diamines and carboxylic acids was developed under microwave irradiation condition, which provided a practical and efficient method for high-throughput synthesis of this important class of heterocyclic compounds.
Cyclic Nucleotide Phosphodiesterase Inhibition by Imidazopyridines: Analogues of Sulmazole and Isomazole as Inhibitors of the cGMP Specific Phosphodiesterase
Coates, William J.,Connolly, Brendan,Dhanak, Dashyant,Flynn, Sean T.,Worby, Angela
, p. 1387 - 1392 (2007/10/02)
The synthesis and phosphodiesterase (PDE) inhibitory profile of a series of imidazopyridines, including sulmazole and isomazole, on separated PDE isoenzymes are described.The results show that both sulmazole and isomazole are weak inhibitors of PDE III, and their inotropic activity is unlikely to be due to PDE III inhibition alone.Surprisingly, both compounds were found to be significant inhibitors of the cGMP specific isoenzyme, PDE V, and a series of simple 2-substituted phenylimidazopyridines have been made to investigate the SAR of PDE activity.This has been shown to be sensitive to chain length, polarity, and the nature of the heteroatom linking group.Potent PDE V inhibitors, many of which are also significant inhibitors of PDE IV, have been identified.
