24194-09-0

Basic information

• Product Name: 2-(4-chloro-phenylsulfanyl)-ethylamine; hydrochloride
• CAS NO: 24194-09-0
• Molecular Weight: 224.154
• Mol File: 24194-09-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(4-chloro-phenylsulfanyl)-ethylamine; hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-chloro-phenylsulfanyl)-ethylamine; hydrochloride(24194-09-0)
• EPA Substance Registry System: 2-(4-chloro-phenylsulfanyl)-ethylamine; hydrochloride(24194-09-0)

Safety Data

• Hazardous Substances Data: 24194-09-0(Hazardous Substances Data)

Usage

Chemical classification

Derivative of phenethylamine

Classification explanation

Phenethylamine is the parent compound, and the given compound has a chlorine atom attached to a phenylsulfanyl group, making it a derivative.

Chemical structure

Contains a chlorine atom and a phenylsulfanyl group

Structure explanation

The compound's structure is characterized by the presence of a chlorine atom and a phenylsulfanyl group, which is a benzene ring with a sulfur atom and an ethyl group attached.

Hydrochloride form

Enhanced solubility in water

Solubility explanation

The hydrochloride form of the compound is used to improve its solubility in water, making it more convenient to handle in laboratory settings.
5. Research and experimental purposes

Purpose explanation

This chemical compound is primarily used for research and experimental purposes, such as investigating biochemical processes or developing new medications.

Potential applications

Medication development and biochemical investigation

Application explanation

The compound may have potential applications in the development of new medications or as a tool for investigating biochemical processes in the body.

Safety precautions

Proper handling and potential for misuse or harm

Safety explanation

Due to the potential for misuse or harm if not handled properly, it is important to use caution and follow safety protocols when working with this compound.

Upstream product

• 151-56-4 ethyleneimine 
• 106-54-7 p-Chlorothiophenol 
• 2576-47-8 2-bromoethylamine hydrobromide 

Downstream Products

• 85052-88-6 2-(4-chlorophenylsulphonyl)ethanamine hydrochloride 
• 40077-40-5 2-{[2-(4-Chloro-phenylsulfanyl)-ethylamino]-methyl}-3,4-dihydro-2H-naphthalen-1-one 
• 16928-92-0 2-(4-chlorophenylthio)-N,N-dimethylethanamine hydrochloride 
• 104863-96-9 2-(4-chlorophenylsulphoxido)ethanamine hydrochloride 
• 104864-59-7 2-Chloro-N-[2-(4-chloro-phenylsulfanyl)-ethyl]-acetamide 
• 67215-16-1 2-(4-Chloro-benzenesulfinyl)-ethylamine 
• 38752-40-8 p-Chlorphenyl-2-isothiocyanatsulfid 
• 104864-22-4 N-(4-methyl-1-piperazinyl)acetyl-2-(p-chlorophenylthio)ethanamine hydrochloride 

Relevant articles and documents

Synthesis of 2,3,4,5-Tetrahydrobenzo[1,4]thiazepines via N-Acyliminium Cyclization

We report an efficient and scalable synthesis of 7-methoxy-2,3,4,5-tetrahydrobenzo[1,4]thiazepine, the core structure of biologically active molecules like JTV-519 and S107. This synthetic route, starting with 4-methoxythiophenol and proceeding via acyliminum cyclization, gives the target product in four steps and 68% overall yield and is a substantial improvement over previously published processes. Nine additional examples of tetrahydrobenzo[1,4]thiazepine synthesis via acyliminium ring closure are also presented.