24202-75-3Relevant articles and documents
High-yield synthesis method of methyl 4-aminonicotinate
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Paragraph 0024; 0028-0029; 0033; 0037-0038; 0042; 0046-0047, (2021/09/08)
The invention discloses a high-yield synthesis method of methyl 4-aminonicotinate, which comprises the following steps: by taking 3, 4-dipicolinic acid as a raw material, carrying out intramolecular dehydration substitution, ammonia ammonification, improved NBS Hofmann rearrangement and hydrolysis to obtain the methyl 4-aminonicotinate. The synthesis method disclosed by the invention is simpler to operate, mild in reaction condition and higher in total yield, and has an extremely high application value.
Preparation of monoesters of pyridine-dicarboxylic acids
Thunus,Dejardin-Duchene
, p. 3 - 21 (2007/10/04)
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