24214-72-0

Basic information

• Product Name: Cyclopentylhydrazine hydrochloride
• Synonyms: 1-CYCLOPENTYHYDRAZINE HYDROCHLORIDE;1-CYCLOPENTYLHYDRAZINE HYDROCHLORIDE;CYCLOPENTYL HYDRAZINE HYDROCHLORIDE;CyclopentylhydrazineHCl;Hydrazinocyclopentane hydrochloride;1-CYCLOPENTYLHYDRAZINE HCL;cyclopentylhydrazine, HCl salt;cyclopentyl-hydrazinhydrochloride
• CAS NO: 24214-72-0
• Molecular Formula: C₅H₁₂N₂*ClH
• Molecular Weight: 136.62
• Product Categories: Ring Systems
• Mol File: 24214-72-0.mol
• Article Data: 9

Chemical Properties

• Melting Point: 131-132 °C
• Boiling Point: 189.7 °C at 760 mmHg
• Flash Point: 76.1 °C
• Appearance: /
• Density: 0.95g/cm³
• Vapor Pressure: 0.562mmHg at 25°C
• Refractive Index: 1.493
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: Cyclopentylhydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentylhydrazine hydrochloride(24214-72-0)
• EPA Substance Registry System: Cyclopentylhydrazine hydrochloride(24214-72-0)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 24214-72-0(Hazardous Substances Data)

Usage

Uses

Cyclopentylhydrazine Hydrochloride

InChI:InChI=1S/C5H12N2.ClH/c6-7-5-3-1-2-4-5;/h5,7H,1-4,6H2;1H

Upstream product

• 120-92-3 cyclopentanone 
• 287729-05-9 N-cyclopentyl-N-tert-butyloxycarbonylaminophthalimide 
• 96-41-3 Cyclopentanol 
• 79201-39-1 tert-butyl 2-cyclopentylidenehydrazine carboxylate 
• 259870-74-1 tert-butyl 1-cyclopentylhydrazinecarboxylate 
• 646071-31-0 tert-butyl 2-cyclopentylhydrazinecarboxylate 

Downstream Products

• 30241-37-3 1-cyclopentyl-3-methyl-1H-pyrazol-5-amine 
• 30929-67-0 5-amino-1-cyclopentyl-1H-pyrazole-4-carbonitrile 
• 89169-57-3 6-Methoxy-1,2,3,4-tetrahydrocyclopentaindole 
• 1426534-38-4 C₂₁H₂₄N₂O 
• 158001-01-5 1-cyclopentyl-3-phenylmethyl-5-amino-1H-pyrazole-4-carbonitrile 
• 162141-77-7 1-Cyclopentyl-3-ethyl-6-(4-methoxy-phenyl)-1,4,5,6-tetrahydro-pyrazolo[3,4-c]pyridin-7-one 

Relevant articles and documents

Decarboxylative hydrazination of unactivated carboxylic acids by cerium photocatalysis

We report the cerium photocatalyzed radical decarboxylative hydrazination of carboxylic acids with di-tert-butylazodicarboxylate (DBAD). The operationally simple protocol provides rapid access to synthetically useful hydrazine derivatives and overcomes current scope limitations in the photoredox-catalyzed decarboxylation of carboxylic acids.

Adamantyl-pyrazole carboxamides as inhibitors of 11B-hydroxysteroid dehydrogenase

Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, type II diabetes mellitus and metabolic syndrome.

Synthesis, biological evaluation, and structural studies on N1 and C5 substituted cycloalkyl analogues of the pyrazole class of CB1 and CB2 ligands

A series of N1 and C5 substituted cycloalkyl and C5 4-methylphenyl analogues of the N-(piperidin-1-yl)-4-methyl-1H-pyrazole-3-carboxamide class of cannabinoid ligands were synthesized. The analogues were evaluated for CB1 and CB2 receptor binding affinities and receptor subtype selectivity. The effects of pyrazole substitution on ligand conformation and as such receptor affinities was not readily apparent; therefore, the geometries of the N1 and C5 substituents relative to the pyrazole ring were studied using high field NMR spectroscopy and systematic molecular mechanics geometry searches. An analysis of the relative ring geometries and functional group orientations provides new insight into the structural requirements of the CB1 and CB2 ligand binding pocket.